Ling K - Search Results

1

An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis.

Gertsman I, Wuu J, McAlonis-Downes M, Ghassemian M, Ling K, Rigo F, Bennett F, Benatar M, Miller TM, Da Cruz S. Gertsman I, et al. Among authors: ling k. JCI Insight. 2019 May 16;4(10):e122768. doi: 10.1172/jci.insight.122768. eCollection 2019 May 16. JCI Insight. 2019. PMID: 31092730 Free PMC article.

2

Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.

Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M Jr, Burge CB, Taylor JP, Rigo F, Yeo GW. Martinez FJ, et al. Among authors: ling k. Neuron. 2016 Nov 23;92(4):780-795. doi: 10.1016/j.neuron.2016.09.050. Epub 2016 Oct 20. Neuron. 2016. PMID: 27773581 Free PMC article.

3

The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.

d'Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, Ling K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, Sumner CJ. d'Ydewalle C, et al. Among authors: ling k. Neuron. 2017 Jan 4;93(1):66-79. doi: 10.1016/j.neuron.2016.11.033. Epub 2016 Dec 22. Neuron. 2017. PMID: 28017471 Free PMC article.

4

Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.

Fil D, DeLoach A, Yadav S, Alkam D, MacNicol M, Singh A, Compadre CM, Goellner JJ, O'Brien CA, Fahmi T, Basnakian AG, Calingasan NY, Klessner JL, Beal FM, Peters OM, Metterville J, Brown RH Jr, Ling KKY, Rigo F, Ozdinler PH, Kiaei M. Fil D, et al. Among authors: ling kky. Hum Mol Genet. 2017 Feb 15;26(4):686-701. doi: 10.1093/hmg/ddw429. Hum Mol Genet. 2017. PMID: 28040732 Free PMC article.

5

Antisense-mediated reduction of EphA4 in the adult CNS does not improve the function of mice with amyotrophic lateral sclerosis.

Ling KK, Jackson M, Alkam D, Liu D, Allaire N, Sun C, Kiaei M, McCampbell A, Rigo F. Ling KK, et al. Neurobiol Dis. 2018 Jun;114:174-183. doi: 10.1016/j.nbd.2018.03.002. Epub 2018 Mar 6. Neurobiol Dis. 2018. PMID: 29518482 Free PMC article.

6

NCALD Antisense Oligonucleotide Therapy in Addition to Nusinersen further Ameliorates Spinal Muscular Atrophy in Mice.

Torres-Benito L, Schneider S, Rombo R, Ling KK, Grysko V, Upadhyay A, Kononenko NL, Rigo F, Bennett CF, Wirth B. Torres-Benito L, et al. Among authors: ling kk. Am J Hum Genet. 2019 Jul 3;105(1):221-230. doi: 10.1016/j.ajhg.2019.05.008. Epub 2019 Jun 20. Am J Hum Genet. 2019. PMID: 31230718 Free PMC article.

7

Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS.

Ghadge GD, Sonobe Y, Camarena A, Drigotas C, Rigo F, Ling KK, Roos RP. Ghadge GD, et al. Among authors: ling kk. Neurobiol Dis. 2020 Mar;136:104702. doi: 10.1016/j.nbd.2019.104702. Epub 2019 Dec 16. Neurobiol Dis. 2020. PMID: 31837419 Free article.

8

Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination.

Lai F, Damle SS, Ling KK, Rigo F. Lai F, et al. Among authors: ling kk. Mol Cell. 2020 Mar 5;77(5):1032-1043.e4. doi: 10.1016/j.molcel.2019.12.029. Epub 2020 Jan 7. Mol Cell. 2020. PMID: 31924447 Free article.

9

Tau seeds are subject to aberrant modifications resulting in distinct signatures.

Tseng JH, Ajit A, Tabassum Z, Patel N, Tian X, Chen Y, Prevatte AW, Ling K, Rigo F, Meeker RB, Herring LE, Cohen TJ. Tseng JH, et al. Among authors: ling k. Cell Rep. 2021 Apr 27;35(4):109037. doi: 10.1016/j.celrep.2021.109037. Cell Rep. 2021. PMID: 33910013 Free PMC article.

10

Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB.

Maimon R, Chillon-Marinas C, Snethlage CE, Singhal SM, McAlonis-Downes M, Ling K, Rigo F, Bennett CF, Da Cruz S, Hnasko TS, Muotri AR, Cleveland DW. Maimon R, et al. Among authors: ling k. Nat Neurosci. 2021 Aug;24(8):1089-1099. doi: 10.1038/s41593-021-00864-y. Epub 2021 Jun 3. Nat Neurosci. 2021. PMID: 34083786 Free PMC article.

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