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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E; DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank); EADB (Alzheimer Disease European DNA biobank); IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium); IPDGC (The International Parkinson Disease Genomics Consortium); RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia); Netherlands Brain Bank (NBB); Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kaw… See abstract for full author list ➔ van der Lee SJ, et al. Among authors: wagner m. Acta Neuropathol. 2019 Aug;138(2):237-250. doi: 10.1007/s00401-019-02026-8. Epub 2019 May 27. Acta Neuropathol. 2019. PMID: 31131421 Free PMC article.
Anticholinergic drug use and risk for dementia: target for dementia prevention.
Jessen F, Kaduszkiewicz H, Daerr M, Bickel H, Pentzek M, Riedel-Heller S, Wagner M, Weyerer S, Wiese B, van den Bussche H, Broich K, Maier W. Jessen F, et al. Among authors: wagner m. Eur Arch Psychiatry Clin Neurosci. 2010 Nov;260 Suppl 2:S111-5. doi: 10.1007/s00406-010-0156-4. Epub 2010 Oct 20. Eur Arch Psychiatry Clin Neurosci. 2010. PMID: 20960005
Impact of TCF4 on the genetics of schizophrenia.
Lennertz L, Quednow BB, Benninghoff J, Wagner M, Maier W, Mössner R. Lennertz L, et al. Among authors: wagner m. Eur Arch Psychiatry Clin Neurosci. 2011 Nov;261 Suppl 2:S161-5. doi: 10.1007/s00406-011-0256-9. Epub 2011 Sep 20. Eur Arch Psychiatry Clin Neurosci. 2011. PMID: 21932083 Free article. Review.
AD dementia risk in late MCI, in early MCI, and in subjective memory impairment.
Jessen F, Wolfsgruber S, Wiese B, Bickel H, Mösch E, Kaduszkiewicz H, Pentzek M, Riedel-Heller SG, Luck T, Fuchs A, Weyerer S, Werle J, van den Bussche H, Scherer M, Maier W, Wagner M; German Study on Aging, Cognition and Dementia in Primary Care Patients. Jessen F, et al. Among authors: wagner m. Alzheimers Dement. 2014 Jan;10(1):76-83. doi: 10.1016/j.jalz.2012.09.017. Epub 2013 Jan 30. Alzheimers Dement. 2014. PMID: 23375567
Depression, non-fatal stroke and all-cause mortality in old age: a prospective cohort study of primary care patients.
Köhler S, Verhey F, Weyerer S, Wiese B, Heser K, Wagner M, Pentzek M, Fuchs A, Köhler M, Bachmann C, Riedel Heller SG, Luppa M, Eifflaender-Gorfer S, Werle J, Bickel H, Mösch E, König HH, Brettschneider C, Scherer M, Maier W. Köhler S, et al. Among authors: wagner m. J Affect Disord. 2013 Aug 15;150(1):63-9. doi: 10.1016/j.jad.2013.02.020. Epub 2013 Mar 7. J Affect Disord. 2013. PMID: 23474092 Free article.
6,524 results