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Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation.
Sashindranath M, Samson AL, Downes CE, Crack PJ, Lawrence AJ, Li QX, Ng AQ, Jones NC, Farrugia JJ, Abdella E, Vassalli JD, Madani R, Medcalf RL. Sashindranath M, et al. Among authors: medcalf rl. Lab Invest. 2011 Jul;91(7):1079-91. doi: 10.1038/labinvest.2011.67. Epub 2011 Apr 25. Lab Invest. 2011. PMID: 21519332 Free article.
The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.
Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL. Sashindranath M, et al. Among authors: medcalf rl. Brain. 2012 Nov;135(Pt 11):3251-64. doi: 10.1093/brain/aws178. Epub 2012 Jul 20. Brain. 2012. PMID: 22822039 Free PMC article.
Tissue plasminogen activator does not alter development of acquired epilepsy.
Tan ML, Ng A, Pandher PS, Sashindranath M, Hamilton JA, Davis SM, O'Brien TJ, Medcalf RL, Yan B, Jones NC. Tan ML, et al. Among authors: medcalf rl. Epilepsia. 2012 Nov;53(11):1998-2004. doi: 10.1111/j.1528-1167.2012.03635.x. Epub 2012 Sep 7. Epilepsia. 2012. PMID: 22957978 Free article.
Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.
Samson AL, Knaupp AS, Sashindranath M, Borg RJ, Au AE, Cops EJ, Saunders HM, Cody SH, McLean CA, Nowell CJ, Hughes VA, Bottomley SP, Medcalf RL. Samson AL, et al. Among authors: medcalf rl. Cell Rep. 2012 Oct 25;2(4):889-901. doi: 10.1016/j.celrep.2012.08.026. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041318 Free article.
Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes.
Crack PJ, Zhang M, Morganti-Kossmann MC, Morris AJ, Wojciak JM, Fleming JK, Karve I, Wright D, Sashindranath M, Goldshmit Y, Conquest A, Daglas M, Johnston LA, Medcalf RL, Sabbadini RA, Pébay A. Crack PJ, et al. Among authors: medcalf rl. J Neuroinflammation. 2014 Feb 27;11:37. doi: 10.1186/1742-2094-11-37. J Neuroinflammation. 2014. PMID: 24576351 Free PMC article.
The fibrinolytic system-more than fibrinolysis?
Draxler DF, Medcalf RL. Draxler DF, et al. Among authors: medcalf rl. Transfus Med Rev. 2015 Apr;29(2):102-9. doi: 10.1016/j.tmrv.2014.09.006. Epub 2014 Dec 18. Transfus Med Rev. 2015. PMID: 25576010 Review.
178 results