Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G.
Zhang Y, et al. Among authors: zhang j.
FASEB J. 2017 Dec;31(12):5342-5355. doi: 10.1096/fj.201700351R. Epub 2017 Aug 9.
FASEB J. 2017.
PMID: 28794173
These findings suggest that Tph1 mediates the compensation of islet function induced by glucose, and that promoting Tph1 expression in pancreatic beta cells will provide a new strategy for the treatment of type 2 diabetes mellitus.-Zhang, Y., Deng, R., Yang, X., Xu, …
These findings suggest that Tph1 mediates the compensation of islet function induced by glucose, and that promoting Tph1 expression in pancr …