Liu DR - Search Results

1

Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.

Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR. Huang TP, et al. Among authors: liu dr. Nat Biotechnol. 2019 Jul;37(7):820. doi: 10.1038/s41587-019-0168-1. Nat Biotechnol. 2019. PMID: 31182863

2

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. Pattanayak V, et al. Among authors: liu dr. Nat Biotechnol. 2013 Sep;31(9):839-43. doi: 10.1038/nbt.2673. Epub 2013 Aug 11. Nat Biotechnol. 2013. PMID: 23934178 Free PMC article.

3

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.

Guilinger JP, Thompson DB, Liu DR. Guilinger JP, et al. Among authors: liu dr. Nat Biotechnol. 2014 Jun;32(6):577-582. doi: 10.1038/nbt.2909. Epub 2014 Apr 25. Nat Biotechnol. 2014. PMID: 24770324 Free PMC article.

4

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Kim YB, et al. Among authors: liu dr. Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13. Nat Biotechnol. 2017. PMID: 28191901 Free PMC article.

5

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Komor AC, et al. Among authors: liu dr. Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28875174 Free PMC article.

6

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Gaudelli NM, et al. Among authors: liu dr. Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. Nature. 2017. PMID: 29160308 Free PMC article.

7

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR. Hu JH, et al. Among authors: liu dr. Nature. 2018 Apr 5;556(7699):57-63. doi: 10.1038/nature26155. Epub 2018 Feb 28. Nature. 2018. PMID: 29512652 Free PMC article.

8

Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Gaudelli NM, et al. Among authors: liu dr. Nature. 2018 Jul;559(7714):E8. doi: 10.1038/s41586-018-0070-x. Nature. 2018. PMID: 29720650

9

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.

Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Koblan LW, et al. Among authors: liu dr. Nat Biotechnol. 2018 Oct;36(9):843-846. doi: 10.1038/nbt.4172. Epub 2018 May 29. Nat Biotechnol. 2018. PMID: 29813047 Free PMC article.

10

Continuous directed evolution of proteins with improved soluble expression.

Wang T, Badran AH, Huang TP, Liu DR. Wang T, et al. Among authors: liu dr. Nat Chem Biol. 2018 Oct;14(10):972-980. doi: 10.1038/s41589-018-0121-5. Epub 2018 Aug 20. Nat Chem Biol. 2018. PMID: 30127387 Free PMC article.

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