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Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.
Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, Baba T, Takeda A, Kanzaki M, Wakabayashi K, Okano H, Aoki M. Kobayashi J, et al. Among authors: tomiyama a. FASEB J. 2019 Sep;33(9):10240-10256. doi: 10.1096/fj.201802051R. Epub 2019 Jun 18. FASEB J. 2019. PMID: 31211923
Moreover, we demonstrated that alpha-SYN itself exploited the DAT endocytic process to enter dopaminergic neuron-like cells, and both FLOT1 and DAT were found to be the components of LBs. Altogether, these findings revealed a novel role of extracellular alpha-SYN on cellul …
Moreover, we demonstrated that alpha-SYN itself exploited the DAT endocytic process to enter dopaminergic neuron-like cells, and both FLOT1 …
Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression.
Kitanaka C, Kato K, Ijiri R, Sakurada K, Tomiyama A, Noguchi K, Nagashima Y, Nakagawara A, Momoi T, Toyoda Y, Kigasawa H, Nishi T, Shirouzu M, Yokoyama S, Tanaka Y, Kuchino Y. Kitanaka C, et al. Among authors: tomiyama a. J Natl Cancer Inst. 2002 Mar 6;94(5):358-68. doi: 10.1093/jnci/94.5.358. J Natl Cancer Inst. 2002. PMID: 11880474
Downregulation of Ras C-terminal processing by JNK inhibition.
Mouri W, Tachibana K, Tomiyama A, Sunayama J, Sato A, Sakurada K, Kayama T, Kitanaka C. Mouri W, et al. Among authors: tomiyama a. Biochem Biophys Res Commun. 2008 Jun 27;371(2):273-7. doi: 10.1016/j.bbrc.2008.04.057. Epub 2008 Apr 22. Biochem Biophys Res Commun. 2008. PMID: 18435909
Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR.
Sato A, Sunayama J, Matsuda K, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C. Sato A, et al. Among authors: tomiyama a. Neurosci Lett. 2010 Feb 12;470(2):115-20. doi: 10.1016/j.neulet.2009.12.067. Epub 2010 Jan 1. Neurosci Lett. 2010. PMID: 20045038
239 results