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Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production.
Kakoki M, Bahnson EM, Hagaman JR, Siletzky RM, Grant R, Kayashima Y, Li F, Lee EY, Sun MT, Taylor JM, Rice JC, Almeida MF, Bahr BA, Jennette JC, Smithies O, Maeda-Smithies N. Kakoki M, et al. Among authors: smithies o. JCI Insight. 2019 Jun 20;4(12):e127660. doi: 10.1172/jci.insight.127660. eCollection 2019 Jun 20. JCI Insight. 2019. PMID: 31217360 Free PMC article.
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Kakoki M, Pochynyuk OM, Hathaway CM, Tomita H, Hagaman JR, Kim HS, Zaika OL, Mamenko M, Kayashima Y, Matsuki K, Hiller S, Li F, Xu L, Grant R, Bertorello AM, Smithies O. Kakoki M, et al. Among authors: smithies o. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5600-5. doi: 10.1073/pnas.1302641110. Epub 2013 Mar 15. Proc Natl Acad Sci U S A. 2013. PMID: 23503843 Free PMC article.
Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade.
Hathaway CK, Grant R, Hagaman JR, Hiller S, Li F, Xu L, Chang AS, Madden VJ, Bagnell CR, Rojas M, Kim HS, Wu B, Zhou B, Smithies O, Kakoki M. Hathaway CK, et al. Among authors: smithies o. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5141-6. doi: 10.1073/pnas.1504557112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848038 Free PMC article.
Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
Kakoki M, Sullivan KA, Backus C, Hayes JM, Oh SS, Hua K, Gasim AM, Tomita H, Grant R, Nossov SB, Kim HS, Jennette JC, Feldman EL, Smithies O. Kakoki M, et al. Among authors: smithies o. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10190-5. doi: 10.1073/pnas.1005144107. Epub 2010 May 17. Proc Natl Acad Sci U S A. 2010. PMID: 20479236 Free PMC article.
343 results