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Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: cotugno g. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2. Nat Commun. 2019. PMID: 31217437 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Among authors: cotugno g. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723
Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion.
D'Alise AM, Leoni G, De Lucia M, Langone F, Nocchi L, Tucci FG, Micarelli E, Cotugno G, Troise F, Garzia I, Vitale R, Bignone V, Di Matteo E, Bartolomeo R, Charych DH, Lahm A, Zalevsky J, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: cotugno g. J Immunother Cancer. 2021 Nov;9(11):e003480. doi: 10.1136/jitc-2021-003480. J Immunother Cancer. 2021. PMID: 34824160 Free PMC article.
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment.
De Lucia M, Cotugno G, Bignone V, Garzia I, Nocchi L, Langone F, Petrovic B, Sasso E, Pepe S, Froechlich G, Gentile C, Zambrano N, Campadelli-Fiume G, Nicosia A, Scarselli E, D'Alise AM. De Lucia M, et al. Among authors: cotugno g. Mol Ther Oncolytics. 2020 Oct 14;19:253-264. doi: 10.1016/j.omto.2020.10.006. eCollection 2020 Dec 16. Mol Ther Oncolytics. 2020. PMID: 33209980 Free PMC article.
Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus.
Froechlich G, Caiazza C, Gentile C, D'Alise AM, De Lucia M, Langone F, Leoni G, Cotugno G, Scisciola V, Nicosia A, Scarselli E, Mallardo M, Sasso E, Zambrano N. Froechlich G, et al. Among authors: cotugno g. Cancers (Basel). 2020 Nov 17;12(11):3407. doi: 10.3390/cancers12113407. Cancers (Basel). 2020. PMID: 33213060 Free PMC article.
VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens' Prediction.
Leoni G, D'Alise AM, Tucci FG, Micarelli E, Garzia I, De Lucia M, Langone F, Nocchi L, Cotugno G, Bartolomeo R, Romano G, Allocca S, Troise F, Nicosia A, Lahm A, Scarselli E. Leoni G, et al. Among authors: cotugno g. Vaccines (Basel). 2021 Aug 9;9(8):880. doi: 10.3390/vaccines9080880. Vaccines (Basel). 2021. PMID: 34452005 Free PMC article.
Inhibition of ocular neovascularization by hedgehog blockade.
Surace EM, Balaggan KS, Tessitore A, Mussolino C, Cotugno G, Bonetti C, Vitale A, Ali RR, Auricchio A. Surace EM, et al. Among authors: cotugno g. Mol Ther. 2006 Mar;13(3):573-9. doi: 10.1016/j.ymthe.2005.10.010. Epub 2005 Dec 15. Mol Ther. 2006. PMID: 16343995 Free article.
66 results