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Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial.
Tap WD, Gelderblom H, Palmerini E, Desai J, Bauer S, Blay JY, Alcindor T, Ganjoo K, Martín-Broto J, Ryan CW, Thomas DM, Peterfy C, Healey JH, van de Sande M, Gelhorn HL, Shuster DE, Wang Q, Yver A, Hsu HH, Lin PS, Tong-Starksen S, Stacchiotti S, Wagner AJ; ENLIVEN investigators. Tap WD, et al. Among authors: van de sande m. Lancet. 2019 Aug 10;394(10197):478-487. doi: 10.1016/S0140-6736(19)30764-0. Epub 2019 Jun 19. Lancet. 2019. PMID: 31229240 Free PMC article. Clinical Trial.
Current concepts in the treatment of giant cell tumour of bone.
van der Heijden L, Dijkstra S, van de Sande M, Gelderblom H. van der Heijden L, et al. Among authors: van de sande m. Curr Opin Oncol. 2020 Jul;32(4):332-338. doi: 10.1097/CCO.0000000000000645. Curr Opin Oncol. 2020. PMID: 32541321 Review.
Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.
Yin O, Wagner AJ, Kang J, Knebel W, Zahir H, van de Sande M, Tap WD, Gelderblom H, Healey JH, Shuster D, Stacchiotti S. Yin O, et al. Among authors: van de sande m. J Clin Pharmacol. 2021 Apr;61(4):480-492. doi: 10.1002/jcph.1753. Epub 2020 Oct 11. J Clin Pharmacol. 2021. PMID: 33043474 Free PMC article. Clinical Trial.
Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial.
Van De Sande M, Tap WD, Gelhorn HL, Ye X, Speck RM, Palmerini E, Stacchiotti S, Desai J, Wagner AJ, Alcindor T, Ganjoo K, Martín-Broto J, Wang Q, Shuster D, Gelderblom H, Healey JH. Van De Sande M, et al. Acta Orthop. 2021 Aug;92(4):493-499. doi: 10.1080/17453674.2021.1922161. Epub 2021 May 12. Acta Orthop. 2021. PMID: 33977825 Free PMC article. Clinical Trial.
Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
Yin O, Zahir H, French J, Polhamus D, Wang X, van de Sande M, Tap WD, Gelderblom H, Wagner AJ, Healey JH, Greenberg J, Shuster D, Stacchiotti S. Yin O, et al. Among authors: van de sande m. CPT Pharmacometrics Syst Pharmacol. 2021 Nov;10(11):1422-1432. doi: 10.1002/psp4.12712. Epub 2021 Oct 14. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34585528 Free PMC article.
Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
Healey JH, Tap WD, Gelhorn HL, Ye X, Speck RM, Palmerini E, Stacchiotti S, Desai J, Wagner AJ, Alcindor T, Ganjoo K, Martín-Broto J, Wang Q, Shuster D, Gelderblom H, van de Sande M. Healey JH, et al. Among authors: van de sande m. Clin Orthop Relat Res. 2023 Jan 1;481(1):107-116. doi: 10.1097/CORR.0000000000002335. Epub 2022 Aug 24. Clin Orthop Relat Res. 2023. PMID: 36001000 Free PMC article. Clinical Trial.
A prospective real-world study of the diffuse-type tenosynovial giant cell tumor patient journey: A 2-year observational analysis.
Bernthal NM, Healey JH, Palmerini E, Bauer S, Schreuder H, Leithner A, Martin-Broto J, Gouin F, Lopez-Bastida J, Gelderblom H, Staals EL, Burke ZD, Geiger EJ, Spierenburg G, Laeis P, Beyerlein E, Ye X, van de Sande M. Bernthal NM, et al. Among authors: van de sande m. J Surg Oncol. 2022 Dec;126(8):1520-1532. doi: 10.1002/jso.27067. Epub 2022 Aug 25. J Surg Oncol. 2022. PMID: 36006054 Free PMC article.
360 results