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Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD.
Storek KM, Chan J, Vij R, Chiang N, Lin Z, Bevers J 3rd, Koth CM, Vernes JM, Meng YG, Yin J, Wallweber H, Dalmas O, Shriver S, Tam C, Schneider K, Seshasayee D, Nakamura G, Smith PA, Payandeh J, Koerber JT, Comps-Agrar L, Rutherford ST. Storek KM, et al. Among authors: shriver s. Elife. 2019 Jun 25;8:e46258. doi: 10.7554/eLife.46258. Elife. 2019. PMID: 31237236 Free PMC article.
Engineering an APRIL-specific B cell maturation antigen.
Patel DR, Wallweber HJ, Yin J, Shriver SK, Marsters SA, Gordon NC, Starovasnik MA, Kelley RF. Patel DR, et al. J Biol Chem. 2004 Apr 16;279(16):16727-35. doi: 10.1074/jbc.M312316200. Epub 2004 Feb 4. J Biol Chem. 2004. PMID: 14764606 Free article.
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist.
Ahuja S, Mukund S, Deng L, Khakh K, Chang E, Ho H, Shriver S, Young C, Lin S, Johnson JP Jr, Wu P, Li J, Coons M, Tam C, Brillantes B, Sampang H, Mortara K, Bowman KK, Clark KR, Estevez A, Xie Z, Verschoof H, Grimwood M, Dehnhardt C, Andrez JC, Focken T, Sutherlin DP, Safina BS, Starovasnik MA, Ortwine DF, Franke Y, Cohen CJ, Hackos DH, Koth CM, Payandeh J. Ahuja S, et al. Among authors: shriver s. Science. 2015 Dec 18;350(6267):aac5464. doi: 10.1126/science.aac5464. Science. 2015. PMID: 26680203
Structural basis for dual-mode inhibition of the ABC transporter MsbA.
Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Ho H, et al. Among authors: shriver s. Nature. 2018 May;557(7704):196-201. doi: 10.1038/s41586-018-0083-5. Epub 2018 May 2. Nature. 2018. PMID: 29720648
Semiautomated Small-Scale Purification Method for High-Throughput Expression Analysis of Recombinant Proteins.
Kraft E, Franke Y, Heeringa K, Shriver S, Zilberleyb I, Kugel C, Dela Vega T, Wong A, Brillantes B, Ciferri C, Dutina G, Lee G, Lehoux I, Li ZR, Lior-Hoffmann L, Hwang J, Lonergan C, Martin L, Mortara K, Nguyen L, Payandeh J, Perez A, Sampang J, Singh L, Schroeder K, Tam C, Ti S, Win YN, Bowman K. Kraft E, et al. Among authors: shriver s. Methods Mol Biol. 2019;2025:51-68. doi: 10.1007/978-1-4939-9624-7_3. Methods Mol Biol. 2019. PMID: 31267448
The discovery and structural basis of two distinct state-dependent inhibitors of BamA.
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J. Sun D, et al. Among authors: shriver s. Nat Commun. 2024 Oct 8;15(1):8718. doi: 10.1038/s41467-024-52512-1. Nat Commun. 2024. PMID: 39379361 Free PMC article.
ICEBERG: a novel inhibitor of interleukin-1beta generation.
Humke EW, Shriver SK, Starovasnik MA, Fairbrother WJ, Dixit VM. Humke EW, et al. Among authors: shriver sk. Cell. 2000 Sep 29;103(1):99-111. doi: 10.1016/s0092-8674(00)00108-2. Cell. 2000. PMID: 11051551 Free article.
47 results