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Page 1
Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia.
Brown LM, Bartolo RC, Davidson NM, Schmidt B, Brooks I, Challis J, Petrovic V, Khuong-Quang DA, Mechinaud F, Khaw SL, Majewski IJ, Oshlack A, Ekert PG. Brown LM, et al. Among authors: khaw sl. Pediatr Blood Cancer. 2019 Oct;66(10):e27897. doi: 10.1002/pbc.27897. Epub 2019 Jun 28. Pediatr Blood Cancer. 2019. PMID: 31250523
Dysregulation of BCL-2 family proteins by leukemia fusion genes.
Brown LM, Hanna DT, Khaw SL, Ekert PG. Brown LM, et al. Among authors: khaw sl. J Biol Chem. 2017 Sep 1;292(35):14325-14333. doi: 10.1074/jbc.R117.799056. Epub 2017 Jul 17. J Biol Chem. 2017. PMID: 28717011 Free PMC article. Review.
Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions.
Meyer C, Lopes BA, Caye-Eude A, Cavé H, Arfeuille C, Cuccuini W, Sutton R, Venn NC, Oh SH, Tsaur G, Escherich G, Feuchtinger T, Kosasih HJ, Khaw SL, Ekert PG, Pombo-de-Oliveira MS, Bidet A, Djahanschiri B, Ebersberger I, Zaliova M, Zuna J, Zermanova Z, Juvonen V, Grümayer RP, Fazio G, Cazzaniga G, Larghero P, Emerenciano M, Marschalek R. Meyer C, et al. Among authors: khaw sl. Leukemia. 2019 Sep;33(9):2306-2340. doi: 10.1038/s41375-019-0451-7. Epub 2019 Mar 21. Leukemia. 2019. PMID: 30899083 Free PMC article. No abstract available.
The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia.
Brown LM, Lonsdale A, Zhu A, Davidson NM, Schmidt B, Hawkins A, Wallach E, Martin M, Mechinaud FM, Khaw SL, Bartolo RC, Ludlow LEA, Challis J, Brooks I, Petrovic V, Venn NC, Sutton R, Majewski IJ, Oshlack A, Ekert PG. Brown LM, et al. Among authors: khaw sl. Blood Adv. 2020 Mar 10;4(5):930-942. doi: 10.1182/bloodadvances.2019001008. Blood Adv. 2020. PMID: 32150610 Free PMC article.
Cotargeting BCL-2 and MCL-1 in high-risk B-ALL.
Moujalled DM, Hanna DT, Hediyeh-Zadeh S, Pomilio G, Brown L, Litalien V, Bartolo R, Fleming S, Chanrion M, Banquet S, Maragno AL, Kraus-Berthier L, Schoumacher M, Mullighan CG, Georgiou A, White CA, Lessene G, Huang DCS, Roberts AW, Geneste O, Rasmussen L, Davis MJ, Ekert PG, Wei A, Ng AP, Khaw SL. Moujalled DM, et al. Among authors: khaw sl. Blood Adv. 2020 Jun 23;4(12):2762-2767. doi: 10.1182/bloodadvances.2019001416. Blood Adv. 2020. PMID: 32569380 Free PMC article.
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.
Wong M, Mayoh C, Lau LMS, Khuong-Quang DA, Pinese M, Kumar A, Barahona P, Wilkie EE, Sullivan P, Bowen-James R, Syed M, Martincorena I, Abascal F, Sherstyuk A, Bolanos NA, Baber J, Priestley P, Dolman MEM, Fleuren EDG, Gauthier ME, Mould EVA, Gayevskiy V, Gifford AJ, Grebert-Wade D, Strong PA, Manouvrier E, Warby M, Thomas DM, Kirk J, Tucker K, O'Brien T, Alvaro F, McCowage GB, Dalla-Pozza L, Gottardo NG, Tapp H, Wood P, Khaw SL, Hansford JR, Moore AS, Norris MD, Trahair TN, Lock RB, Tyrrell V, Haber M, Marshall GM, Ziegler DS, Ekert PG, Cowley MJ. Wong M, et al. Among authors: khaw sl. Nat Med. 2020 Nov;26(11):1742-1753. doi: 10.1038/s41591-020-1072-4. Epub 2020 Oct 5. Nat Med. 2020. PMID: 33020650
MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia.
Kosasih HJ, Davidson NM, Bjelosevic S, Morrish E, Brennan MS, Oshlack A, Johnstone RW, Brumatti G, Khaw SL, Ekert PG. Kosasih HJ, et al. Among authors: khaw sl. Blood Adv. 2020 Oct 13;4(19):4918-4923. doi: 10.1182/bloodadvances.2020002708. Blood Adv. 2020. PMID: 33035331 Free PMC article.
Cycling without brakes lets ALL escape.
Khaw SL, Ekert P. Khaw SL, et al. Blood. 2021 Nov 18;138(20):1912-1913. doi: 10.1182/blood.2021012754. Blood. 2021. PMID: 34792574 Free article. No abstract available.
43 results