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Targeting skeletal endothelium to ameliorate bone loss.
Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Xu R, et al. Among authors: li n. Nat Med. 2018 Jun;24(6):823-833. doi: 10.1038/s41591-018-0020-z. Epub 2018 May 21. Nat Med. 2018. PMID: 29785024 Free PMC article.
Discovery of a periosteal stem cell mediating intramembranous bone formation.
Debnath S, Yallowitz AR, McCormick J, Lalani S, Zhang T, Xu R, Li N, Liu Y, Yang YS, Eiseman M, Shim JH, Hameed M, Healey JH, Bostrom MP, Landau DA, Greenblatt MB. Debnath S, et al. Among authors: li n. Nature. 2018 Oct;562(7725):133-139. doi: 10.1038/s41586-018-0554-8. Epub 2018 Sep 24. Nature. 2018. PMID: 30250253 Free PMC article.
Osteoclasts are not a source of SLIT3.
Li N, Inoue K, Sun J, Niu Y, Lalani S, Yallowitz A, Yang X, Zhang C, Shen R, Zhao B, Xu R, Greenblatt MB. Li N, et al. Bone Res. 2020 Feb 19;8:11. doi: 10.1038/s41413-020-0086-3. eCollection 2020. Bone Res. 2020. PMID: 32133214 Free PMC article.
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. Kim JM, et al. Among authors: li n. Nat Commun. 2020 May 8;11(1):2289. doi: 10.1038/s41467-020-16038-6. Nat Commun. 2020. PMID: 32385263 Free PMC article.
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.
Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. Bok S, et al. Among authors: li n. Nat Commun. 2020 Nov 11;11(1):5704. doi: 10.1038/s41467-020-19555-6. Nat Commun. 2020. PMID: 33177525 Free PMC article.
SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts.
Sun J, Shin DY, Eiseman M, Yallowitz AR, Li N, Lalani S, Li Z, Cung M, Bok S, Debnath S, Marquez SJ, White TE, Khan AG, Lorenz IC, Shim JH, Lee FS, Xu R, Greenblatt MB. Sun J, et al. Among authors: li z, li n. Nat Commun. 2021 Jul 29;12(1):4611. doi: 10.1038/s41467-021-24819-w. Nat Commun. 2021. PMID: 34326333 Free PMC article.
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