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Scalable Workflows and Reproducible Data Analysis for Genomics.
Strozzi F, Janssen R, Wurmus R, Crusoe MR, Githinji G, Di Tommaso P, Belhachemi D, Möller S, Smant G, de Ligt J, Prins P. Strozzi F, et al. Among authors: janssen r. Methods Mol Biol. 2019;1910:723-745. doi: 10.1007/978-1-4939-9074-0_24. Methods Mol Biol. 2019. PMID: 31278683 Free PMC article.
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer.
Christensen S, Van der Roest B, Besselink N, Janssen R, Boymans S, Martens JWM, Yaspo ML, Priestley P, Kuijk E, Cuppen E, Van Hoeck A. Christensen S, et al. Among authors: janssen r. Nat Commun. 2019 Oct 8;10(1):4571. doi: 10.1038/s41467-019-12594-8. Nat Commun. 2019. PMID: 31594944 Free PMC article.
The mutational impact of culturing human pluripotent and adult stem cells.
Kuijk E, Jager M, van der Roest B, Locati MD, Van Hoeck A, Korzelius J, Janssen R, Besselink N, Boymans S, van Boxtel R, Cuppen E. Kuijk E, et al. Among authors: janssen r. Nat Commun. 2020 May 19;11(1):2493. doi: 10.1038/s41467-020-16323-4. Nat Commun. 2020. PMID: 32427826 Free PMC article.
Prioritization of genes driving congenital phenotypes of patients with de novo genomic structural variants.
Middelkamp S, Vlaar JM, Giltay J, Korzelius J, Besselink N, Boymans S, Janssen R, de la Fonteijne L, van Binsbergen E, van Roosmalen MJ, Hochstenbach R, Giachino D, Talkowski ME, Kloosterman WP, Cuppen E. Middelkamp S, et al. Among authors: janssen r. Genome Med. 2019 Dec 4;11(1):79. doi: 10.1186/s13073-019-0692-0. Genome Med. 2019. PMID: 31801603 Free PMC article.
Precancerous liver diseases do not cause increased mutagenesis in liver stem cells.
Nguyen L, Jager M, Lieshout R, de Ruiter PE, Locati MD, Besselink N, van der Roest B, Janssen R, Boymans S, de Jonge J, IJzermans JNM, Doukas M, Verstegen MMA, van Boxtel R, van der Laan LJW, Cuppen E, Kuijk E. Nguyen L, et al. Among authors: janssen r. Commun Biol. 2021 Nov 18;4(1):1301. doi: 10.1038/s42003-021-02839-y. Commun Biol. 2021. PMID: 34795391 Free PMC article.
1,010 results