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User-defined single pot mutagenesis using unamplified oligo pools.
Medina-Cucurella AV, Steiner PJ, Faber MS, Beltrán J, Borelli AN, Kirby MB, Cutler SR, Whitehead TA. Medina-Cucurella AV, et al. Among authors: cutler sr. Protein Eng Des Sel. 2019 Sep 10;32(1):41-45. doi: 10.1093/protein/gzz013. Protein Eng Des Sel. 2019. PMID: 31297523 Free PMC article.
Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.
Beltrán J, Steiner PJ, Bedewitz M, Wei S, Peterson FC, Li Z, Hughes BE, Hartley Z, Robertson NR, Medina-Cucurella AV, Baumer ZT, Leonard AC, Park SY, Volkman BF, Nusinow DA, Zhong W, Wheeldon I, Cutler SR, Whitehead TA. Beltrán J, et al. Among authors: cutler sr. Nat Biotechnol. 2022 Dec;40(12):1855-1861. doi: 10.1038/s41587-022-01364-5. Epub 2022 Jun 20. Nat Biotechnol. 2022. PMID: 35726092 Free PMC article.
An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.
Park SY, Qiu J, Wei S, Peterson FC, Beltrán J, Medina-Cucurella AV, Vaidya AS, Xing Z, Volkman BF, Nusinow DA, Whitehead TA, Wheeldon I, Cutler SR. Park SY, et al. Among authors: cutler sr. Nat Chem Biol. 2024 Jan;20(1):103-110. doi: 10.1038/s41589-023-01447-7. Epub 2023 Oct 23. Nat Chem Biol. 2024. PMID: 37872402 Free PMC article.
Structural mechanism of abscisic acid binding and signaling by dimeric PYR1.
Nishimura N, Hitomi K, Arvai AS, Rambo RP, Hitomi C, Cutler SR, Schroeder JI, Getzoff ED. Nishimura N, et al. Among authors: cutler sr. Science. 2009 Dec 4;326(5958):1373-9. doi: 10.1126/science.1181829. Epub 2009 Oct 22. Science. 2009. PMID: 19933100 Free PMC article.
Plant genome engineering in full bloom.
Lozano-Juste J, Cutler SR. Lozano-Juste J, et al. Among authors: cutler sr. Trends Plant Sci. 2014 May;19(5):284-7. doi: 10.1016/j.tplants.2014.02.014. Epub 2014 Mar 24. Trends Plant Sci. 2014. PMID: 24674878
Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Vaidya AS, Peterson FC, Eckhardt J, Xing Z, Park SY, Dejonghe W, Takeuchi J, Pri-Tal O, Faria J, Elzinga D, Volkman BF, Todoroki Y, Mosquna A, Okamoto M, Cutler SR. Vaidya AS, et al. Among authors: cutler sr. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2108281118. doi: 10.1073/pnas.2108281118. Proc Natl Acad Sci U S A. 2021. PMID: 34531324 Free PMC article.
Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.
Park SY, Fung P, Nishimura N, Jensen DR, Fujii H, Zhao Y, Lumba S, Santiago J, Rodrigues A, Chow TF, Alfred SE, Bonetta D, Finkelstein R, Provart NJ, Desveaux D, Rodriguez PL, McCourt P, Zhu JK, Schroeder JI, Volkman BF, Cutler SR. Park SY, et al. Among authors: cutler sr. Science. 2009 May 22;324(5930):1068-71. doi: 10.1126/science.1173041. Epub 2009 Apr 30. Science. 2009. PMID: 19407142 Free PMC article.
87 results