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Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block.
Diez V, Loznik M, Taylor S, Winn M, Rattray NJ, Podmore H, Micklefield J, Goodacre R, Medema MH, Müller U, Bovenberg R, Janssen DB, Takano E. Diez V, et al. Among authors: micklefield j. ACS Synth Biol. 2015 Jul 17;4(7):796-807. doi: 10.1021/sb500368w. Epub 2015 Mar 9. ACS Synth Biol. 2015. PMID: 25713978
Minimum Information about a Biosynthetic Gene cluster.
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R… See abstract for full author list ➔ Medema MH, et al. Among authors: micklefield j. Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. Nat Chem Biol. 2015. PMID: 26284661 Free PMC article. No abstract available.
SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.
Carbonell P, Currin A, Dunstan M, Fellows D, Jervis A, Rattray NJ, Robinson CJ, Swainston N, Vinaixa M, Williams A, Yan C, Barran P, Breitling R, Chen GG, Faulon JL, Goble C, Goodacre R, Kell DB, Feuvre RL, Micklefield J, Scrutton NS, Shapira P, Takano E, Turner NJ. Carbonell P, et al. Among authors: micklefield j. Biochem Soc Trans. 2016 Jun 15;44(3):675-7. doi: 10.1042/BST20160009. Biochem Soc Trans. 2016. PMID: 27284023 Free PMC article.
Development of Halogenase Enzymes for Use in Synthesis.
Latham J, Brandenburger E, Shepherd SA, Menon BRK, Micklefield J. Latham J, et al. Among authors: micklefield j. Chem Rev. 2018 Jan 10;118(1):232-269. doi: 10.1021/acs.chemrev.7b00032. Epub 2017 May 3. Chem Rev. 2018. PMID: 28466644 Review.
RadH: A Versatile Halogenase for Integration into Synthetic Pathways.
Menon BRK, Brandenburger E, Sharif HH, Klemstein U, Shepherd SA, Greaney MF, Micklefield J. Menon BRK, et al. Among authors: micklefield j. Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11841-11845. doi: 10.1002/anie.201706342. Epub 2017 Aug 18. Angew Chem Int Ed Engl. 2017. PMID: 28722773 Free PMC article.
94 results