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UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER.
Denaxas S, Gonzalez-Izquierdo A, Direk K, Fitzpatrick NK, Fatemifar G, Banerjee A, Dobson RJB, Howe LJ, Kuan V, Lumbers RT, Pasea L, Patel RS, Shah AD, Hingorani AD, Sudlow C, Hemingway H. Denaxas S, et al. Among authors: lumbers rt. J Am Med Inform Assoc. 2019 Dec 1;26(12):1545-1559. doi: 10.1093/jamia/ocz105. J Am Med Inform Assoc. 2019. PMID: 31329239 Free PMC article.
CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research.
Kotecha D, Asselbergs FW, Achenbach S, Anker SD, Atar D, Baigent C, Banerjee A, Beger B, Brobert G, Casadei B, Ceccarelli C, Cowie MR, Crea F, Cronin M, Denaxas S, Derix A, Fitzsimons D, Fredriksson M, Gale CP, Gkoutos GV, Goettsch W, Hemingway H, Ingvar M, Jonas A, Kazmierski R, Løgstrup S, Thomas Lumbers R, Lüscher TF, McGreavy P, Piña IL, Roessig L, Steinbeisser C, Sundgren M, Tyl B, van Thiel G, van Bochove K, Vardas PE, Villanueva T, Vrana M, Weber W, Weidinger F, Windecker S, Wood A, Grobbee DE; Innovative Medicines Initiative BigData@Heart Consortium, European Society of Cardiology, CODE-EHR international consensus group. Kotecha D, et al. Eur Heart J. 2022 Oct 7;43(37):3578-3588. doi: 10.1093/eurheartj/ehac426. Eur Heart J. 2022. PMID: 36208161 Free PMC article.
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience.
Jurgens SJ, Rämö JT, Kramarenko DR, Wijdeveld LFJM, Haas J, Chaffin MD, Garnier S, Gaziano L, Weng LC, Lipov A, Zheng SL, Henry A, Huffman JE, Challa S, Rühle F, Verdugo CD, Krijger Juárez C, Kany S, van Orsouw CA, Biddinger K, Poel E, Elliott AL, Wang X, Francis C, Ruan R, Koyama S, Beekman L, Zimmerman DS, Deleuze JF, Villard E, Trégouët DA, Isnard R; FinnGen; VA Million Veteran Program; HERMES Consortium; Boomsma DI, de Geus EJC, Tadros R, Pinto YM, Wilde AAM, Hottenga JJ, Sinisalo J, Niiranen T, Walsh R, Schmidt AF, Choi SH, Chang KM, Tsao PS, Matthews PM, Ware JS, Lumbers RT, van der Crabben S, Laukkanen J, Palotie A, Amin AS, Charron P, Meder B, Ellinor PT, Daly M, Aragam KG, Bezzina CR. Jurgens SJ, et al. Among authors: lumbers rt. Nat Genet. 2024 Nov 21. doi: 10.1038/s41588-024-01975-5. Online ahead of print. Nat Genet. 2024. PMID: 39572784
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Zheng SL, Henry A, Cannie D, Lee M, Miller D, McGurk KA, Bond I, Xu X, Issa H, Francis C, De Marvao A, Theotokis PI, Buchan RJ, Speed D, Abner E, Adams L, Aragam KG, Ärnlöv J, Raja AA, Backman JD, Baksi J, Barton PJR, Biddinger KJ, Boersma E, Brandimarto J, Brunak S, Bundgaard H, Carey DJ, Charron P, Cook JP, Cook SA, Denaxas S, Deleuze JF, Doney AS, Elliott P, Erikstrup C, Esko T, Farber-Eger EH, Finan C, Garnier S, Ghouse J, Giedraitis V, Guðbjartsson DF, Haggerty CM, Halliday BP, Helgadottir A, Hemingway H, Hillege HL, Kardys I, Lind L, Lindgren CM, Lowery BD, Manisty C, Margulies KB, Moon JC, Mordi IR, Morley MP, Morris AD, Morris AP, Morton L, Noursadeghi M, Ostrowski SR, Owens AT, Palmer CNA, Pantazis A, Pedersen OBV, Prasad SK, Shekhar A, Smelser DT, Srinivasan S, Stefansson K, Sveinbjörnsson G, Syrris P, Tammesoo ML, Tayal U, Teder-Laving M, Thorgeirsson G, Thorsteinsdottir U, Tragante V, Trégouët DA, Treibel TA, Ullum H, Valdes AM, van Setten J, van Vugt M, Veluchamy A, Verschuren WMM, Villard E, Yang Y; COVIDsortium; DBDS Genomic Consortium; Estonian Biobank Research Team; HERMES Consortium; Asselbergs FW, Cappola TP, Dube MP, Dunn ME, Ellinor PT, Hingorani AD, Lang CC, … See abstract for full author list ➔ Zheng SL, et al. Among authors: lumbers rt. Nat Genet. 2024 Nov 21. doi: 10.1038/s41588-024-01952-y. Online ahead of print. Nat Genet. 2024. PMID: 39572783
Genetic and phenotypic architecture of human myocardial trabeculation.
McGurk KA, Qiao M, Zheng SL, Sau A, Henry A, Ribeiro ALP, Ribeiro AH, Ng FS, Lumbers RT, Bai W, Ware JS, O'Regan DP. McGurk KA, et al. Among authors: lumbers rt. Nat Cardiovasc Res. 2024 Nov 20. doi: 10.1038/s44161-024-00564-3. Online ahead of print. Nat Cardiovasc Res. 2024. PMID: 39567769
Gender and contemporary risk of adverse events in atrial fibrillation.
Champsi A, Mobley AR, Subramanian A, Nirantharakumar K, Wang X, Shukla D, Bunting KV, Molgaard I, Dwight J, Arroyo RC, Crijns HJGM, Guasti L, Lettino M, Lumbers RT, Maesen B, Rienstra M, Svennberg E, Țica O, Traykov V, Tzeis S, van Gelder I, Kotecha D. Champsi A, et al. Among authors: lumbers rt. Eur Heart J. 2024 Sep 29;45(36):3707-3717. doi: 10.1093/eurheartj/ehae539. Eur Heart J. 2024. PMID: 39217497 Free PMC article.
2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS).
Van Gelder IC, Rienstra M, Bunting KV, Casado-Arroyo R, Caso V, Crijns HJGM, De Potter TJR, Dwight J, Guasti L, Hanke T, Jaarsma T, Lettino M, Løchen ML, Lumbers RT, Maesen B, Mølgaard I, Rosano GMC, Sanders P, Schnabel RB, Suwalski P, Svennberg E, Tamargo J, Tica O, Traykov V, Tzeis S, Kotecha D; ESC Scientific Document Group. Van Gelder IC, et al. Among authors: lumbers rt. Eur Heart J. 2024 Sep 29;45(36):3314-3414. doi: 10.1093/eurheartj/ehae176. Eur Heart J. 2024. PMID: 39210723 No abstract available.
Rationale and design of the THIRST Alert feasibility study: a pragmatic, single-centre, parallel-group randomised controlled trial of an interruptive alert for oral fluid restriction in patients treated with intravenous furosemide.
Chen Y, Shah A, Jani Y, Higgins D, Saleem N, Chafer K, Sydes MR, Asselbergs FW, Lumbers RT. Chen Y, et al. Among authors: lumbers rt. BMJ Open. 2024 Jan 11;14(1):e080410. doi: 10.1136/bmjopen-2023-080410. BMJ Open. 2024. PMID: 38216198 Free PMC article.
On the estimation of the effect of weight change on a health outcome using observational data, by utilising the target trial emulation framework.
Katsoulis M, Lai AG, Kipourou DK, Gomes M, Banerjee A, Denaxas S, Lumbers RT, Tsilidis K, Kostara M, Belot A, Dale C, Sofat R, Leyrat C, Hemingway H, Diaz-Ordaz K. Katsoulis M, et al. Among authors: lumbers rt. Int J Obes (Lond). 2023 Dec;47(12):1309-1317. doi: 10.1038/s41366-023-01396-0. Epub 2023 Oct 26. Int J Obes (Lond). 2023. PMID: 37884665 Free PMC article.
44 results