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CSF-1 controls cerebellar microglia and is required for motor function and social interaction.
Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M. Kana V, et al. Among authors: sneeboer m. J Exp Med. 2019 Oct 7;216(10):2265-2281. doi: 10.1084/jem.20182037. Epub 2019 Jul 26. J Exp Med. 2019. PMID: 31350310 Free PMC article.
Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated.
Sneeboer MAM, Snijders GJLJ, Berdowski WM, Fernández-Andreu A; Psychiatric Donor Program of the Netherlands Brain Bank (NBB-Psy); van Mierlo HC, Berdenis van Berlekom A, Litjens M, Kahn RS, Hol EM, de Witte LD. Sneeboer MAM, et al. Transl Psychiatry. 2019 May 24;9(1):153. doi: 10.1038/s41398-019-0490-x. Transl Psychiatry. 2019. PMID: 31127084 Free PMC article.
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry.
Böttcher C, Schlickeiser S, Sneeboer MAM, Kunkel D, Knop A, Paza E, Fidzinski P, Kraus L, Snijders GJL, Kahn RS, Schulz AR, Mei HE; NBB-Psy; Hol EM, Siegmund B, Glauben R, Spruth EJ, de Witte LD, Priller J. Böttcher C, et al. Among authors: sneeboer mam. Nat Neurosci. 2019 Jan;22(1):78-90. doi: 10.1038/s41593-018-0290-2. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559476
Distinct non-inflammatory signature of microglia in post-mortem brain tissue of patients with major depressive disorder.
Snijders GJLJ, Sneeboer MAM, Fernández-Andreu A, Udine E; Psychiatric donor program of the Netherlands Brain Bank (NBB-Psy); Boks MP, Ormel PR, van Berlekom AB, van Mierlo HC, Bӧttcher C, Priller J, Raj T, Hol EM, Kahn RS, de Witte LD. Snijders GJLJ, et al. Among authors: sneeboer mam. Mol Psychiatry. 2021 Jul;26(7):3336-3349. doi: 10.1038/s41380-020-00896-z. Epub 2020 Oct 7. Mol Psychiatry. 2021. PMID: 33028963
Microglia innately develop within cerebral organoids.
Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ. Ormel PR, et al. Among authors: sneeboer mam. Nat Commun. 2018 Oct 9;9(1):4167. doi: 10.1038/s41467-018-06684-2. Nat Commun. 2018. PMID: 30301888 Free PMC article.
A loss of mature microglial markers without immune activation in schizophrenia.
Snijders GJLJ, van Zuiden W, Sneeboer MAM, Berdenis van Berlekom A, van der Geest AT, Schnieder T, MacIntyre DJ, Hol EM, Kahn RS, de Witte LD. Snijders GJLJ, et al. Among authors: sneeboer mam. Glia. 2021 May;69(5):1251-1267. doi: 10.1002/glia.23962. Epub 2021 Jan 7. Glia. 2021. PMID: 33410555 Free PMC article.
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease.
Guttikonda SR, Sikkema L, Tchieu J, Saurat N, Walsh RM, Harschnitz O, Ciceri G, Sneeboer M, Mazutis L, Setty M, Zumbo P, Betel D, de Witte LD, Pe'er D, Studer L. Guttikonda SR, et al. Among authors: sneeboer m. Nat Neurosci. 2021 Mar;24(3):343-354. doi: 10.1038/s41593-020-00796-z. Epub 2021 Feb 8. Nat Neurosci. 2021. PMID: 33558694 Free PMC article.
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies.
Lopes KP, Snijders GJL, Humphrey J, Allan A, Sneeboer MAM, Navarro E, Schilder BM, Vialle RA, Parks M, Missall R, van Zuiden W, Gigase FAJ, Kübler R, van Berlekom AB, Hicks EM, Bӧttcher C, Priller J, Kahn RS, de Witte LD, Raj T. Lopes KP, et al. Among authors: sneeboer mam. Nat Genet. 2022 Jan;54(1):4-17. doi: 10.1038/s41588-021-00976-y. Epub 2022 Jan 6. Nat Genet. 2022. PMID: 34992268 Free PMC article.
24 results