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Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3-Knockin Mice.
Burova E, Hermann A, Dai J, Ullman E, Halasz G, Potocky T, Hong S, Liu M, Allbritton O, Woodruff A, Pei J, Rafique A, Poueymirou W, Martin J, MacDonald D, Olson WC, Murphy A, Ioffe E, Thurston G, Mohrs M. Burova E, et al. Among authors: halasz g. Mol Cancer Ther. 2019 Nov;18(11):2051-2062. doi: 10.1158/1535-7163.MCT-18-1376. Epub 2019 Aug 8. Mol Cancer Ther. 2019. PMID: 31395688
The potassium channel Kcne3 is a VEGFA-inducible gene selectively expressed by vascular endothelial tip cells.
Deckelbaum RA, Lobov IB, Cheung E, Halasz G, Rajamani S, Lerner J, Tong C, Li Z, Boland P, Dominguez M, Hughes V, Yancopoulos GD, Murphy AJ, Thurston G, Cao J, Romano C, Gale NW. Deckelbaum RA, et al. Among authors: halasz g. Angiogenesis. 2020 May;23(2):179-192. doi: 10.1007/s10456-019-09696-8. Epub 2019 Nov 21. Angiogenesis. 2020. PMID: 31754927 Free PMC article.
Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy.
Devalaraja-Narashimha K, Meagher K, Luo Y, Huang C, Kaplan T, Muthuswamy A, Halasz G, Casanova S, O'Brien J, Peyser Boiarsky R, McWhirter J, Gartner H, Bai Y, MacDonnell S, Liu C, Hu Y, Latuszek A, Wei Y, Prasad S, Huang T, Yancopoulos G, Murphy A, Olson W, Zambrowicz B, Macdonald L, Morton LG. Devalaraja-Narashimha K, et al. Among authors: halasz g. J Am Soc Nephrol. 2021 Jan;32(1):99-114. doi: 10.1681/ASN.2020050698. Epub 2020 Dec 7. J Am Soc Nephrol. 2021. PMID: 33288630 Free PMC article.
A cellular and molecular spatial atlas of dystrophic muscle.
Stec MJ, Su Q, Adler C, Zhang L, Golann DR, Khan NP, Panagis L, Villalta SA, Ni M, Wei Y, Walls JR, Murphy AJ, Yancopoulos GD, Atwal GS, Kleiner S, Halasz G, Sleeman MW. Stec MJ, et al. Among authors: halasz g. Proc Natl Acad Sci U S A. 2023 Jul 18;120(29):e2221249120. doi: 10.1073/pnas.2221249120. Epub 2023 Jul 6. Proc Natl Acad Sci U S A. 2023. PMID: 37410813 Free PMC article.
Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
Adam RC, Pryce DS, Lee JS, Zhao Y, Mintah IJ, Min S, Halasz G, Mastaitis J, Atwal GS, Aykul S, Idone V, Economides AN, Lotta LA, Murphy AJ, Yancopoulos GD, Sleeman MW, Gusarova V. Adam RC, et al. Among authors: halasz g. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2309967120. doi: 10.1073/pnas.2309967120. Epub 2023 Jul 31. Proc Natl Acad Sci U S A. 2023. PMID: 37523551 Free PMC article.
Divergent role of Mitochondrial Amidoxime Reducing Component 1 (MARC1) in human and mouse.
Smagris E, Shihanian LM, Mintah IJ, Bigdelou P, Livson Y, Brown H, Verweij N, Hunt C, Johnson RO, Greer TJ, Hartford SA, Hindy G, Sun L, Nielsen JB, Halasz G, Lotta LA, Murphy AJ, Sleeman MW, Gusarova V. Smagris E, et al. Among authors: halasz g. PLoS Genet. 2024 Mar 4;20(3):e1011179. doi: 10.1371/journal.pgen.1011179. eCollection 2024 Mar. PLoS Genet. 2024. PMID: 38437227 Free PMC article.
Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development.
MacDonnell S, Megna J, Ruan Q, Zhu O, Halasz G, Jasewicz D, Powers K, E H, Del Pilar Molina-Portela M, Jin X, Zhang D, Torello J, Feric NT, Graziano MP, Shekhar A, Dunn ME, Glass D, Morton L. MacDonnell S, et al. Among authors: halasz g. Front Cardiovasc Med. 2022 Nov 10;9:1038114. doi: 10.3389/fcvm.2022.1038114. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36440002 Free PMC article.
238 results