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Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, Gebauer C, Zhang J, Xu X, Wang J, Croker BA, Frazer KA, Putnam CD, Hoffman HM. Broderick L, et al. Among authors: cowell ig. Nat Commun. 2019 Aug 13;10(1):3644. doi: 10.1038/s41467-019-11570-6. Nat Commun. 2019. PMID: 31409799 Free PMC article.
Self-association of chromo domain peptides.
Cowell IG, Austin CA. Cowell IG, et al. Biochim Biophys Acta. 1997 Feb 8;1337(2):198-206. doi: 10.1016/s0167-4838(96)00165-3. Biochim Biophys Acta. 1997. PMID: 9048896
NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.
Toyoda E, Kagaya S, Cowell IG, Kurosawa A, Kamoshita K, Nishikawa K, Iiizumi S, Koyama H, Austin CA, Adachi N. Toyoda E, et al. Among authors: cowell ig. J Biol Chem. 2008 Aug 29;283(35):23711-20. doi: 10.1074/jbc.M803936200. Epub 2008 Jul 2. J Biol Chem. 2008. PMID: 18596031 Free PMC article.
62 results