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Page 1
Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program.
Janin M, Ortiz-Barahona V, de Moura MC, Martínez-Cardús A, Llinàs-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno-Costa A, Piñeyro D, Perez-Salvia M, Rosselló-Tortella M, Piqué L, Bech-Serra JJ, De La Torre C, Vidal A, Martínez-Iniesta M, Martín-Tejera JF, Villanueva A, Arias A, Cuartas I, Aransay AM, La Madrid AM, Carcaboso AM, Santa-Maria V, Mora J, Fernandez AF, Fraga MF, Aldecoa I, Pedrosa L, Graus F, Vidal N, Martínez-Soler F, Tortosa A, Carrato C, Balañá C, Boudreau MW, Hergenrother PJ, Kötter P, Entian KD, Hench J, Frank S, Mansouri S, Zadeh G, Dans PD, Orozco M, Thomas G, Blanco S, Seoane J, Preiss T, Pandolfi PP, Esteller M. Janin M, et al. Among authors: ortiz barahona v. Acta Neuropathol. 2019 Dec;138(6):1053-1074. doi: 10.1007/s00401-019-02062-4. Epub 2019 Aug 19. Acta Neuropathol. 2019. PMID: 31428936 Free PMC article.
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome.
Esteve-Puig R, Climent F, Piñeyro D, Domingo-Domènech E, Davalos V, Encuentra M, Rea A, Espejo-Herrera N, Soler M, Lopez M, Ortiz-Barahona V, Tapia G, Navarro JT, Cid J, Farré L, Villanueva A, Casanova I, Mangues R, Santamarina-Ojeda P, Fernández AF, Fraga MF, Piris MA, Kol N, Avrahami C, Moshitch-Moshkovitz S, Rechavi G, Sureda A, Esteller M. Esteve-Puig R, et al. Among authors: ortiz barahona v. Blood. 2021 Feb 18;137(7):994-999. doi: 10.1182/blood.2020005823. Blood. 2021. PMID: 32915956 Free PMC article. No abstract available.
Use of DNA methylation profiling in translational oncology.
Ortiz-Barahona V, Joshi RS, Esteller M. Ortiz-Barahona V, et al. Semin Cancer Biol. 2022 Aug;83:523-535. doi: 10.1016/j.semcancer.2020.12.011. Epub 2020 Dec 19. Semin Cancer Biol. 2022. PMID: 33352265 Review.
Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages.
Bueno-Costa A, Piñeyro D, García-Prieto CA, Ortiz-Barahona V, Martinez-Verbo L, Webster NA, Andrews B, Kol N, Avrahami C, Moshitch-Moshkovitz S, Rechavi G, Esteller M. Bueno-Costa A, et al. Among authors: ortiz barahona v. Leukemia. 2022 Aug;36(8):2121-2124. doi: 10.1038/s41375-022-01621-1. Epub 2022 Jun 9. Leukemia. 2022. PMID: 35681051 Free PMC article. No abstract available.
Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer.
Ortiz-Barahona V, Soler M, Davalos V, García-Prieto CA, Janin M, Setien F, Fernández-Rebollo I, Bech-Serra JJ, De La Torre C, Guil S, Villanueva A, Zhang PH, Yang L, Guarnacci M, Schumann U, Preiss T, Balaseviciute U, Montal R, Llovet JM, Esteller M. Ortiz-Barahona V, et al. Mol Cancer. 2023 May 12;22(1):83. doi: 10.1186/s12943-023-01785-z. Mol Cancer. 2023. PMID: 37173708 Free PMC article.
The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis.
Moubarak RS, de Pablos-Aragoneses A, Ortiz-Barahona V, Gong Y, Gowen M, Dolgalev I, Shadaloey SAA, Argibay D, Karz A, Von Itter R, Vega-Sáenz de Miera EC, Sokolova E, Darvishian F, Tsirigos A, Osman I, Hernando E. Moubarak RS, et al. Among authors: ortiz barahona v. Sci Adv. 2022 Feb 18;8(7):eabi7127. doi: 10.1126/sciadv.abi7127. Epub 2022 Feb 18. Sci Adv. 2022. PMID: 35179962 Free PMC article.