Swem L - Search Results

1

Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa.

Krause KM, Haglund CM, Hebner C, Serio AW, Lee G, Nieto V, Cohen F, Kane TR, Machajewski TD, Hildebrandt D, Pillar C, Thwaites M, Hall D, Miesel L, Hackel M, Burek A, Andrews LD, Armstrong E, Swem L, Jubb A, Cirz RT. Krause KM, et al. Among authors: swem l. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00977-19. doi: 10.1128/AAC.00977-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451507 Free PMC article.

2

Preclinical pharmacokinetics of MHAA4549A, a human monoclonal antibody to influenza A virus, and the prediction of its efficacious clinical dose for the treatment of patients hospitalized with influenza A.

Gupta P, Kamath AV, Park S, Chiu H, Lutman J, Maia M, Tan MW, Xu M, Swem L, Deng R. Gupta P, et al. Among authors: swem l. MAbs. 2016 Jul;8(5):991-7. doi: 10.1080/19420862.2016.1167294. Epub 2016 Mar 31. MAbs. 2016. PMID: 27031797 Free PMC article.

3

Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody.

Chai N, Swem LR, Reichelt M, Chen-Harris H, Luis E, Park S, Fouts A, Lupardus P, Wu TD, Li O, McBride J, Lawrence M, Xu M, Tan MW. Chai N, et al. Among authors: swem lr. PLoS Pathog. 2016 Jun 28;12(6):e1005702. doi: 10.1371/journal.ppat.1005702. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27351973 Free PMC article.

4

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action.

Chai N, Swem LR, Park S, Nakamura G, Chiang N, Estevez A, Fong R, Kamen L, Kho E, Reichelt M, Lin Z, Chiu H, Skippington E, Modrusan Z, Stinson J, Xu M, Lupardus P, Ciferri C, Tan MW. Chai N, et al. Among authors: swem lr. Nat Commun. 2017 Jan 19;8:14234. doi: 10.1038/ncomms14234. Nat Commun. 2017. PMID: 28102191 Free PMC article.

5

An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies.

Nakamura G, Chai N, Park S, Chiang N, Lin Z, Chiu H, Fong R, Yan D, Kim J, Zhang J, Lee WP, Estevez A, Coons M, Xu M, Lupardus P, Balazs M, Swem LR. Nakamura G, et al. Among authors: swem lr. Cell Host Microbe. 2013 Jul 17;14(1):93-103. doi: 10.1016/j.chom.2013.06.004. Cell Host Microbe. 2013. PMID: 23870317 Free article.

6

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.

Hazenbos WL, Kajihara KK, Vandlen R, Morisaki JH, Lehar SM, Kwakkenbos MJ, Beaumont T, Bakker AQ, Phung Q, Swem LR, Ramakrishnan S, Kim J, Xu M, Shah IM, Diep BA, Sai T, Sebrell A, Khalfin Y, Oh A, Koth C, Lin SJ, Lee BC, Strandh M, Koefoed K, Andersen PS, Spits H, Brown EJ, Tan MW, Mariathasan S. Hazenbos WL, et al. Among authors: swem lr. PLoS Pathog. 2013;9(10):e1003653. doi: 10.1371/journal.ppat.1003653. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130480 Free PMC article. Clinical Trial.

7

Corrigendum: A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action.

Chai N, Swem LR, Park S, Nakamura G, Chiang N, Estevez A, Fong R, Kamen L, Kho E, Reichelt M, Lin Z, Chiu H, Skippington E, Modrusan Z, Stinson J, Xu M, Lupardus P, Ciferri C, Tan MW. Chai N, et al. Among authors: swem lr. Nat Commun. 2017 May 25;8:15779. doi: 10.1038/ncomms15779. Nat Commun. 2017. PMID: 28541305 Free PMC article.

8

In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells.

Lin Z, Chiang NY, Chai N, Seshasayee D, Lee WP, Balazs M, Nakamura G, Swem LR. Lin Z, et al. Among authors: swem lr. Nat Protoc. 2014 Jul;9(7):1563-77. doi: 10.1038/nprot.2014.104. Epub 2014 Jun 5. Nat Protoc. 2014. PMID: 24901740

9

A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity.

Swem LR, Swem DL, O'Loughlin CT, Gatmaitan R, Zhao B, Ulrich SM, Bassler BL. Swem LR, et al. Among authors: swem dl. Mol Cell. 2009 Jul 31;35(2):143-53. doi: 10.1016/j.molcel.2009.05.029. Mol Cell. 2009. PMID: 19647512 Free PMC article.

10

Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi.

Swem LR, Swem DL, Wingreen NS, Bassler BL. Swem LR, et al. Among authors: swem dl. Cell. 2008 Aug 8;134(3):461-73. doi: 10.1016/j.cell.2008.06.023. Cell. 2008. PMID: 18692469 Free PMC article.

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