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Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.
Jägle S, Rönsch K, Timme S, Andrlová H, Bertrand M, Jäger M, Proske A, Schrempp M, Yousaf A, Michoel T, Zeiser R, Werner M, Lassmann S, Hecht A. Jägle S, et al. Among authors: hecht a. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4886-91. doi: 10.1073/pnas.1314523111. Epub 2014 Mar 18. Proc Natl Acad Sci U S A. 2014. PMID: 24707046 Free PMC article.
SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
Rönsch K, Jägle S, Rose K, Seidl M, Baumgartner F, Freihen V, Yousaf A, Metzger E, Lassmann S, Schüle R, Zeiser R, Michoel T, Hecht A. Rönsch K, et al. Among authors: hecht a. Mol Oncol. 2015 Feb;9(2):335-54. doi: 10.1016/j.molonc.2014.08.016. Epub 2014 Sep 16. Mol Oncol. 2015. PMID: 25277775 Free PMC article.
539 results