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A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J. Bricker DK, et al. Among authors: thummel cs. Science. 2012 Jul 6;337(6090):96-100. doi: 10.1126/science.1218099. Epub 2012 May 24. Science. 2012. PMID: 22628558 Free PMC article.
Methods for studying metabolism in Drosophila.
Tennessen JM, Barry WE, Cox J, Thummel CS. Tennessen JM, et al. Among authors: thummel cs. Methods. 2014 Jun 15;68(1):105-15. doi: 10.1016/j.ymeth.2014.02.034. Epub 2014 Mar 12. Methods. 2014. PMID: 24631891 Free PMC article. Review.
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.
Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J. Schell JC, et al. Among authors: thummel cs. Nat Cell Biol. 2017 Sep;19(9):1027-1036. doi: 10.1038/ncb3593. Epub 2017 Aug 14. Nat Cell Biol. 2017. PMID: 28812582 Free PMC article.
For Intestinal Homeostasis, You Are What You Eat.
Beebe K, Thummel CS. Beebe K, et al. Among authors: thummel cs. Dev Cell. 2018 Oct 8;47(1):1-2. doi: 10.1016/j.devcel.2018.09.018. Dev Cell. 2018. PMID: 30300586 Free PMC article.
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Bensard CL, Wisidagama DR, Olson KA, Berg JA, Krah NM, Schell JC, Nowinski SM, Fogarty S, Bott AJ, Wei P, Dove KK, Tanner JM, Panic V, Cluntun A, Lettlova S, Earl CS, Namnath DF, Vázquez-Arreguín K, Villanueva CJ, Tantin D, Murtaugh LC, Evason KJ, Ducker GS, Thummel CS, Rutter J. Bensard CL, et al. Among authors: thummel cs. Cell Metab. 2020 Feb 4;31(2):284-300.e7. doi: 10.1016/j.cmet.2019.11.002. Epub 2019 Dec 5. Cell Metab. 2020. PMID: 31813825 Free PMC article.
The fate of pyruvate dictates cell growth by modulating cellular redox potential.
Toshniwal AG, Lam G, Bott AJ, Cluntun AA, Skabelund R, Nam HJ, Wisidagama DR, Thummel CS, Rutter J. Toshniwal AG, et al. Among authors: thummel cs. bioRxiv [Preprint]. 2024 Sep 24:2024.09.23.614588. doi: 10.1101/2024.09.23.614588. bioRxiv. 2024. PMID: 39386652 Free PMC article. Preprint.
134 results