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Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose-Range Selection of the Anti-PD-1 Antibody Pembrolizumab.
Lindauer A, Valiathan CR, Mehta K, Sriram V, de Greef R, Elassaiss-Schaap J, de Alwis DP. Lindauer A, et al. Among authors: valiathan cr. CPT Pharmacometrics Syst Pharmacol. 2017 Jan;6(1):11-20. doi: 10.1002/psp4.12130. Epub 2016 Nov 8. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 27863176 Free PMC article.
Atazanavir increases the plasma concentrations of 1200 mg raltegravir dose.
Krishna R, East L, Larson P, Valiathan C, Deschamps K, Luk JA, Bethel-Brown C, Manthos H, Brejda J, Gartner M. Krishna R, et al. Among authors: valiathan c. Biopharm Drug Dispos. 2016 Dec;37(9):533-541. doi: 10.1002/bdd.2043. Epub 2016 Nov 4. Biopharm Drug Dispos. 2016. PMID: 27696440 Clinical Trial.
Model-based meta-analysis of non-small cell lung cancer with standard of care PD-1 inhibitors and chemotherapy for early development decision making.
Turner DC, Wada R, Zhou H, Wang X, de Greef R, Valiathan C, Zhang L, Zhang N, Kuchimanchi M, Chen TT, Ballas M, Visser SAG. Turner DC, et al. Among authors: valiathan c. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1751-1763. doi: 10.1002/psp4.12917. Epub 2023 Jan 31. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36642813 Free PMC article.
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