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Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R.
Mathi GR, Kang CH, Lee HK, Achary R, Lee HY, Lee JY, Ha JD, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Mathi GR, et al. Among authors: lee co, lee jy, lee hy, lee hk. Eur J Med Chem. 2017 Jan 27;126:536-549. doi: 10.1016/j.ejmech.2016.11.046. Epub 2016 Nov 24. Eur J Med Chem. 2017. PMID: 27915169
A simple and sensitive HPLC-FL method for bioanalysis of velpatasvir, a novel hepatitis C virus NS5A inhibitor, in rat plasma: Investigation of factors determining its oral bioavailability.
Choi E, Han DG, Park JE, Lee HY, Yoo JW, Jung Y, Song IS, Yoon IS. Choi E, et al. Among authors: lee hy. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Oct 1;1208:123399. doi: 10.1016/j.jchromb.2022.123399. Epub 2022 Jul 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35921698
Exploring Traits Associated With Central Sensitization Features in Patients With Chronic Cough.
Jun H, Park JY, Oh JY, Won HK, Kang SY, Park SY, Kim BK, Kim MY, Kim YC, Lee HY, Jo EJ, Lee SE, Kim SH, Kim SH, Chang YS, Kim SH, Lee BJ, Chung KF, Song WJ; Korean Chronic Cough Registry Investigators. Jun H, et al. Among authors: lee hy. Allergy Asthma Immunol Res. 2024 Nov;16(6):690-700. doi: 10.4168/aair.2024.16.6.690. Allergy Asthma Immunol Res. 2024. PMID: 39622692 Free article.
BRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK signaling.
Wu S, Deng Y, Sun H, Liu X, Zhou S, Zhao H, Li H, Guo F, Yue Q, Wu F, Zhao X, Li N, Zhu S, Hu Q, Xie S, Zheng J, Lv M, Kong Y, Huang XJ, Lei X, Tong X, Gao X, Lee HY. Wu S, et al. Among authors: lee hy. Signal Transduct Target Ther. 2024 Dec 2;9(1):338. doi: 10.1038/s41392-024-02033-6. Signal Transduct Target Ther. 2024. PMID: 39617757 Free article.
5,450 results