Abbott DW - Search Results

1

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST. Zammit NW, et al. Among authors: abbott dw. Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18. Nat Immunol. 2019. PMID: 31534238

2

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.

Shembade N, Pujari R, Harhaj NS, Abbott DW, Harhaj EW. Shembade N, et al. Among authors: abbott dw. Nat Immunol. 2011 Jul 17;12(9):834-43. doi: 10.1038/ni.2066. Nat Immunol. 2011. PMID: 21765415 Free PMC article.

3

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.

Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J. Dziedzic SA, et al. Among authors: abbott dw. Nat Cell Biol. 2018 Jan;20(1):58-68. doi: 10.1038/s41556-017-0003-1. Epub 2017 Dec 4. Nat Cell Biol. 2018. PMID: 29203883 Free PMC article.

4

An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.

Perez JM, Chirieleison SM, Abbott DW. Perez JM, et al. Among authors: abbott dw. Cell Rep. 2015 Jul 28;12(4):537-44. doi: 10.1016/j.celrep.2015.06.050. Epub 2015 Jul 16. Cell Rep. 2015. PMID: 26190110 Free PMC article.

5

Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase.

Perez JM, Chen Y, Xiao TS, Abbott DW. Perez JM, et al. Among authors: abbott dw. J Biol Chem. 2018 Jan 19;293(3):1100-1105. doi: 10.1074/jbc.RA117.000408. Epub 2017 Dec 6. J Biol Chem. 2018. PMID: 29212706 Free PMC article.

6

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.

Rathkey JK, Zhao J, Liu Z, Chen Y, Yang J, Kondolf HC, Benson BL, Chirieleison SM, Huang AY, Dubyak GR, Xiao TS, Li X, Abbott DW. Rathkey JK, et al. Among authors: abbott dw. Sci Immunol. 2018 Aug 24;3(26):eaat2738. doi: 10.1126/sciimmunol.aat2738. Sci Immunol. 2018. PMID: 30143556 Free PMC article.

7

Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice.

Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K. Gorfu G, et al. Among authors: abbott dw. J Immunol. 2010 Nov 1;185(9):5561-8. doi: 10.4049/jimmunol.0903938. Epub 2010 Oct 6. J Immunol. 2010. PMID: 20926792 Free PMC article.

8

TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

Liu YC, Simmons DP, Li X, Abbott DW, Boom WH, Harding CV. Liu YC, et al. Among authors: abbott dw. J Immunol. 2012 Feb 1;188(3):1019-26. doi: 10.4049/jimmunol.1102181. Epub 2012 Jan 6. J Immunol. 2012. PMID: 22227568 Free PMC article.

9

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F. Corridoni D, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16999-7004. doi: 10.1073/pnas.1311657110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082103 Free PMC article.

10

Myeloid glycosylation defects lead to a spontaneous common variable immunodeficiency-like condition with associated hemolytic anemia and antilymphocyte autoimmunity.

Ryan SO, Abbott DW, Cobb BA. Ryan SO, et al. Among authors: abbott dw. J Immunol. 2014 Jun 15;192(12):5561-70. doi: 10.4049/jimmunol.1400385. Epub 2014 May 2. J Immunol. 2014. PMID: 24795453 Free PMC article.

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