Comstock ML - Search Results

1

γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma.

Pont MJ, Hill T, Cole GO, Abbott JJ, Kelliher J, Salter AI, Hudecek M, Comstock ML, Rajan A, Patel BKR, Voutsinas JM, Wu Q, Liu L, Cowan AJ, Wood BL, Green DJ, Riddell SR. Pont MJ, et al. Among authors: comstock ml. Blood. 2019 Nov 7;134(19):1585-1597. doi: 10.1182/blood.2019000050. Blood. 2019. PMID: 31558469 Free PMC article.

2

CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies.

Green DJ, O'Steen S, Lin Y, Comstock ML, Kenoyer AL, Hamlin DK, Wilbur DS, Fisher DR, Nartea M, Hylarides MD, Gopal AK, Gooley TA, Orozco JJ, Till BG, Orcutt KD, Wittrup KD, Press OW. Green DJ, et al. Among authors: comstock ml. Blood. 2018 Feb 8;131(6):611-620. doi: 10.1182/blood-2017-09-807610. Epub 2017 Nov 20. Blood. 2018. PMID: 29158362 Free PMC article.

3

The α-emitter astatine-211 targeted to CD38 can eradicate multiple myeloma in a disseminated disease model.

O'Steen S, Comstock ML, Orozco JJ, Hamlin DK, Wilbur DS, Jones JC, Kenoyer A, Nartea ME, Lin Y, Miller BW, Gooley TA, Tuazon SA, Till BG, Gopal AK, Sandmaier BM, Press OW, Green DJ. O'Steen S, et al. Among authors: comstock ml. Blood. 2019 Oct 10;134(15):1247-1256. doi: 10.1182/blood.2019001250. Blood. 2019. PMID: 31395601 Free PMC article.

4

Development of [²¹¹At]astatine-based anti-CD123 radioimmunotherapy for acute leukemias and other CD123+ malignancies.

Laszlo GS, Orozco JJ, Kehret AR, Lunn MC, Huo J, Hamlin DK, Scott Wilbur D, Dexter SL, Comstock ML, O'Steen S, Sandmaier BM, Green DJ, Walter RB. Laszlo GS, et al. Among authors: comstock ml. Leukemia. 2022 Jun;36(6):1485-1491. doi: 10.1038/s41375-022-01580-7. Epub 2022 Apr 26. Leukemia. 2022. PMID: 35474099 Free PMC article.

5

Acquired CD38 gene deletion as a mechanism of tumor antigen escape in multiple myeloma.

Portuguese AJ, Fang M, Tuazon SA, Pont M, Qu X, Shasha C, Comstock M, Lyons J, Cole G, Newell EW, Glynn E, Soma LA, Green DJ. Portuguese AJ, et al. Blood Adv. 2023 Dec 12;7(23):7235-7238. doi: 10.1182/bloodadvances.2023011295. Blood Adv. 2023. PMID: 37844282 Free PMC article. No abstract available.

6

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation.

Takahashi S, Minnie SA, Ensbey KS, Schmidt CR, Sekiguchi T, Legg SRW, Zhang P, Koyama M, Olver SD, Collinge AD, Keshmiri S, Comstock ML, Varelias A, Green DJ, Hill GR. Takahashi S, et al. Among authors: comstock ml. Blood. 2024 Apr 18;143(16):1656-1669. doi: 10.1182/blood.2023022000. Blood. 2024. PMID: 38295333 Free PMC article.

7

TIM-3⁺ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.

Minnie SA, Waltner OG, Zhang P, Takahashi S, Nemychenkov NS, Ensbey KS, Schmidt CR, Legg SRW, Comstock M, Boiko JR, Nelson E, Bhise SS, Wilkens AB, Koyama M, Dhodapkar MV, Chesi M, Riddell SR, Green DJ, Spencer A, Furlan SN, Hill GR. Minnie SA, et al. Sci Immunol. 2024 Apr 19;9(94):eadg1094. doi: 10.1126/sciimmunol.adg1094. Epub 2024 Apr 19. Sci Immunol. 2024. PMID: 38640253 Free PMC article.

8

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy.

Coffey DG, Atilla PA, Atilla E, Landgren O, Cowan AJ, Simon S, Pont M, Comstock ML, Hill GR, Riddell SR, Green DJ. Coffey DG, et al. Among authors: comstock ml. Blood. 2024 Oct 7:blood.2024025231. doi: 10.1182/blood.2024025231. Online ahead of print. Blood. 2024. PMID: 39374522 Free article.

9

Kinetics of nirogacestat-mediated increases in B-cell maturation antigen on plasma cells inform therapeutic combinations in multiple myeloma.

Shearer T, Comstock M, Williams RL, Johnson MC, Cendrowicz E, Leonowens C, Smith M, Baughman TM, Breitbach CJ, Cheng S, Green DJ. Shearer T, et al. Cancer Res Commun. 2024 Nov 11. doi: 10.1158/2767-9764.CRC-24-0075. Online ahead of print. Cancer Res Commun. 2024. PMID: 39530736 Free article.

10

A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E.

Rubin BP, Antonescu CR, Scott-Browne JP, Comstock ML, Gu Y, Tanas MR, Ware CB, Woodell J. Rubin BP, et al. Among authors: comstock ml. Cancer Res. 2005 Aug 1;65(15):6631-9. doi: 10.1158/0008-5472.CAN-05-0891. Cancer Res. 2005. PMID: 16061643

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