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Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development.
Fania L, Morelli M, Scarponi C, Mercurio L, Scopelliti F, Cattani C, Scaglione GL, Tonanzi T, Pilla MA, Pagnanelli G, Mazzanti C, Girolomoni G, Cavani A, Madonna S, Albanesi C. Fania L, et al. Among authors: morelli m. J Pathol Clin Res. 2020 Jan;6(1):55-68. doi: 10.1002/cjp2.147. Epub 2019 Oct 29. J Pathol Clin Res. 2020. PMID: 31577850 Free PMC article.
IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment.
Mercurio L, Morelli M, Scarponi C, Eisenmesser EZ, Doti N, Pagnanelli G, Gubinelli E, Mazzanti C, Cavani A, Ruvo M, Dinarello CA, Albanesi C, Madonna S. Mercurio L, et al. Among authors: morelli m. Cell Death Dis. 2018 Oct 30;9(11):1104. doi: 10.1038/s41419-018-1143-3. Cell Death Dis. 2018. PMID: 30377293 Free PMC article.
IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema.
Lauffer F, Jargosch M, Baghin V, Krause L, Kempf W, Absmaier-Kijak M, Morelli M, Madonna S, Marsais F, Lepescheux L, Albanesi C, Müller NS, Theis FJ, Schmidt-Weber C, Eyerich S, Biedermann T, Vandeghinste N, Steidl S, Eyerich K. Lauffer F, et al. Among authors: morelli m. J Eur Acad Dermatol Venereol. 2020 Apr;34(4):800-809. doi: 10.1111/jdv.16126. Epub 2020 Jan 19. J Eur Acad Dermatol Venereol. 2020. PMID: 31793105
Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21.
Mercurio L, Lulli D, Mascia F, Dellambra E, Scarponi C, Morelli M, Valente C, Carbone ML, Pallotta S, Girolomoni G, Albanesi C, Pastore S, Madonna S. Mercurio L, et al. Among authors: morelli m. Aging (Albany NY). 2020 Apr 17;12(8):6823-6851. doi: 10.18632/aging.103045. Epub 2020 Apr 17. Aging (Albany NY). 2020. PMID: 32302288 Free PMC article.
HLA-Cw6 and other HLA-C alleles, as well as MICB-DT, DDX58, and TYK2 genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis.
Morelli M, Galluzzo M, Madonna S, Scarponi C, Scaglione GL, Galluccio T, Andreani M, Pallotta S, Girolomoni G, Bianchi L, Talamonti M, Albanesi C. Morelli M, et al. Expert Opin Biol Ther. 2021 Feb;21(2):259-270. doi: 10.1080/14712598.2021.1862082. Epub 2020 Dec 28. Expert Opin Biol Ther. 2021. PMID: 33297781
1,140 results