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Page 1
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia.
Del Papa B, Baldoni S, Dorillo E, De Falco F, Rompietti C, Cecchini D, Cantelmi MG, Sorcini D, Nogarotto M, Adamo FM, Mezzasoma F, Silva Barcelos EC, Albi E, Iacucci Ostini R, Di Tommaso A, Marra A, Montanaro G, Martelli MP, Falzetti F, Di Ianni M, Rosati E, Sportoletti P. Del Papa B, et al. Among authors: cecchini d. Clin Cancer Res. 2019 Dec 15;25(24):7540-7553. doi: 10.1158/1078-0432.CCR-19-1009. Epub 2019 Oct 2. Clin Cancer Res. 2019. PMID: 31578228
Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.
Del Papa B, Sportoletti P, Cecchini D, Rosati E, Balucani C, Baldoni S, Fettucciari K, Marconi P, Martelli MF, Falzetti F, Di Ianni M. Del Papa B, et al. Among authors: cecchini d. Eur J Immunol. 2013 Jan;43(1):182-7. doi: 10.1002/eji.201242643. Epub 2012 Dec 5. Eur J Immunol. 2013. PMID: 23161436 Free article.
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia.
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, Sorcini D, Varasano E, Cecchini D, Zei T, Di Tommaso A, Rosati E, Alexe G, Roti G, Stegmaier K, Di Ianni M, Falzetti F, Sportoletti P. Baldoni S, et al. Among authors: cecchini d. Int J Cancer. 2018 Aug 15;143(4):958-970. doi: 10.1002/ijc.31355. Epub 2018 Mar 23. Int J Cancer. 2018. PMID: 29508386 Free PMC article.
NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status.
Baldoni S, Del Papa B, De Falco F, Dorillo E, Sorrentino C, Rompietti C, Adamo FM, Nogarotto M, Cecchini D, Mondani E, Silva Barcelos EC, Moretti L, Mameli MG, Fabi B, Sorcini D, Stella A, Giancola R, Guardalupi F, Ulbar F, Plebani S, Guarente V, Rosati E, Di Nicola M, Marchioni M, Di Ianni M, Sportoletti P. Baldoni S, et al. Among authors: cecchini d. Front Oncol. 2021 May 26;11:668573. doi: 10.3389/fonc.2021.668573. eCollection 2021. Front Oncol. 2021. PMID: 34123837 Free PMC article.
The NOTCH1/CD39 axis: a Treg trip-switch for GvHD.
Del Papa B, Pierini A, Sportoletti P, Baldoni S, Cecchini D, Rosati E, Dorillo E, Aureli P, Zei T, Iacucci Ostini R, Ruggeri L, Carotti A, Velardi A, Negrin R, Martelli MF, Falzetti F, Di Ianni M. Del Papa B, et al. Among authors: cecchini d. Leukemia. 2016 Sep;30(9):1931-4. doi: 10.1038/leu.2016.87. Epub 2016 Apr 29. Leukemia. 2016. PMID: 27125307 No abstract available.
Clinical-Grade-Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell-Dependent Graft-versus-Leukemia Effect in Murine Models.
Del Papa B, Ruggeri L, Urbani E, Baldoni S, Cecchini D, Zei T, Iacucci Ostini R, Crescenzi B, Carotti A, Pierini A, Sportoletti P, Di Bartolomeo P, Falzetti F, Mecucci C, Velardi A, Martelli MF, Di Ianni M. Del Papa B, et al. Among authors: cecchini d. Biol Blood Marrow Transplant. 2017 Nov;23(11):1847-1851. doi: 10.1016/j.bbmt.2017.07.009. Epub 2017 Jul 17. Biol Blood Marrow Transplant. 2017. PMID: 28729148 Free article.
GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations.
Sportoletti P, Celani L, Varasano E, Rossi R, Sorcini D, Rompietti C, Strozzini F, Del Papa B, Guarente V, Spinozzi G, Cecchini D, Bereshchenko O, Haferlach T, Martelli MP, Falzetti F, Falini B. Sportoletti P, et al. Among authors: cecchini d. Leukemia. 2019 Jul;33(7):1827-1832. doi: 10.1038/s41375-019-0399-7. Epub 2019 Feb 12. Leukemia. 2019. PMID: 30755706 Free PMC article. No abstract available.
Mesenchymal cells recruit and regulate T regulatory cells.
Di Ianni M, Del Papa B, De Ioanni M, Moretti L, Bonifacio E, Cecchini D, Sportoletti P, Falzetti F, Tabilio A. Di Ianni M, et al. Among authors: cecchini d. Exp Hematol. 2008 Mar;36(3):309-18. doi: 10.1016/j.exphem.2007.11.007. Exp Hematol. 2008. PMID: 18279718 Free article.
CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.
Martelli MP, Pettirossi V, Thiede C, Bonifacio E, Mezzasoma F, Cecchini D, Pacini R, Tabarrini A, Ciurnelli R, Gionfriddo I, Manes N, Rossi R, Giunchi L, Oelschlägel U, Brunetti L, Gemei M, Delia M, Specchia G, Liso A, Di Ianni M, Di Raimondo F, Falzetti F, Del Vecchio L, Martelli MF, Falini B. Martelli MP, et al. Among authors: cecchini d. Blood. 2010 Nov 11;116(19):3907-22. doi: 10.1182/blood-2009-08-238899. Epub 2010 Jul 15. Blood. 2010. PMID: 20634376 Free article.
T regulatory cell separation for clinical application.
Di Ianni M, Del Papa B, Zei T, Iacucci Ostini R, Cecchini D, Cantelmi MG, Baldoni S, Sportoletti P, Cavalli L, Carotti A, Pierini A, Falini B, Martelli MF, Falzetti F. Di Ianni M, et al. Among authors: cecchini d. Transfus Apher Sci. 2012 Oct;47(2):213-6. doi: 10.1016/j.transci.2012.06.007. Epub 2012 Jul 12. Transfus Apher Sci. 2012. PMID: 22795999 Review.
110 results