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Page 1
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia.
Del Papa B, Baldoni S, Dorillo E, De Falco F, Rompietti C, Cecchini D, Cantelmi MG, Sorcini D, Nogarotto M, Adamo FM, Mezzasoma F, Silva Barcelos EC, Albi E, Iacucci Ostini R, Di Tommaso A, Marra A, Montanaro G, Martelli MP, Falzetti F, Di Ianni M, Rosati E, Sportoletti P. Del Papa B, et al. Among authors: rompietti c. Clin Cancer Res. 2019 Dec 15;25(24):7540-7553. doi: 10.1158/1078-0432.CCR-19-1009. Epub 2019 Oct 2. Clin Cancer Res. 2019. PMID: 31578228
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia.
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, Sorcini D, Varasano E, Cecchini D, Zei T, Di Tommaso A, Rosati E, Alexe G, Roti G, Stegmaier K, Di Ianni M, Falzetti F, Sportoletti P. Baldoni S, et al. Among authors: rompietti c. Int J Cancer. 2018 Aug 15;143(4):958-970. doi: 10.1002/ijc.31355. Epub 2018 Mar 23. Int J Cancer. 2018. PMID: 29508386 Free PMC article.
NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells.
Di Ianni M, Baldoni S, Del Papa B, Aureli P, Dorillo E, De Falco F, Albi E, Varasano E, Di Tommaso A, Giancola R, Accorsi P, Rotta G, Rompietti C, Silva Barcelos EC, Campese AF, Di Bartolomeo P, Screpanti I, Rosati E, Falzetti F, Sportoletti P. Di Ianni M, et al. Among authors: rompietti c. Front Oncol. 2018 Apr 20;8:105. doi: 10.3389/fonc.2018.00105. eCollection 2018. Front Oncol. 2018. PMID: 29732315 Free PMC article.
NOTCH1 Aberrations in Chronic Lymphocytic Leukemia.
Rosati E, Baldoni S, De Falco F, Del Papa B, Dorillo E, Rompietti C, Albi E, Falzetti F, Di Ianni M, Sportoletti P. Rosati E, et al. Among authors: rompietti c. Front Oncol. 2018 Jun 27;8:229. doi: 10.3389/fonc.2018.00229. eCollection 2018. Front Oncol. 2018. PMID: 29998084 Free PMC article. Review.
GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations.
Sportoletti P, Celani L, Varasano E, Rossi R, Sorcini D, Rompietti C, Strozzini F, Del Papa B, Guarente V, Spinozzi G, Cecchini D, Bereshchenko O, Haferlach T, Martelli MP, Falzetti F, Falini B. Sportoletti P, et al. Among authors: rompietti c. Leukemia. 2019 Jul;33(7):1827-1832. doi: 10.1038/s41375-019-0399-7. Epub 2019 Feb 12. Leukemia. 2019. PMID: 30755706 Free PMC article. No abstract available.
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
Marchesini M, Gherli A, Montanaro A, Patrizi L, Sorrentino C, Pagliaro L, Rompietti C, Kitara S, Heit S, Olesen CE, Møller JV, Savi M, Bocchi L, Vilella R, Rizzi F, Baglione M, Rastelli G, Loiacono C, La Starza R, Mecucci C, Stegmaier K, Aversa F, Stilli D, Lund Winther AM, Sportoletti P, Bublitz M, Dalby-Brown W, Roti G. Marchesini M, et al. Among authors: rompietti c. Cell Chem Biol. 2020 Jun 18;27(6):678-697.e13. doi: 10.1016/j.chembiol.2020.04.002. Epub 2020 May 7. Cell Chem Biol. 2020. PMID: 32386594 Free PMC article.
NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models.
Baldoni S, Ruggeri L, Del Papa B, Sorcini D, Guardalupi F, Ulbar F, Marra A, Dorillo E, Stella A, Giancola R, Fabi B, Sola R, Ciardelli S, De Falco F, Rompietti C, Adamo FM, Rosati E, Pierini A, Sorrentino C, Sportoletti P, Di Ianni M. Baldoni S, et al. Among authors: rompietti c. Bone Marrow Transplant. 2021 Aug;56(8):2019-2023. doi: 10.1038/s41409-021-01297-8. Epub 2021 Apr 19. Bone Marrow Transplant. 2021. PMID: 33875813 No abstract available.
NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status.
Baldoni S, Del Papa B, De Falco F, Dorillo E, Sorrentino C, Rompietti C, Adamo FM, Nogarotto M, Cecchini D, Mondani E, Silva Barcelos EC, Moretti L, Mameli MG, Fabi B, Sorcini D, Stella A, Giancola R, Guardalupi F, Ulbar F, Plebani S, Guarente V, Rosati E, Di Nicola M, Marchioni M, Di Ianni M, Sportoletti P. Baldoni S, et al. Among authors: rompietti c. Front Oncol. 2021 May 26;11:668573. doi: 10.3389/fonc.2021.668573. eCollection 2021. Front Oncol. 2021. PMID: 34123837 Free PMC article.
NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications.
Sportoletti P, De Falco F, Del Papa B, Baldoni S, Guarente V, Marra A, Dorillo E, Rompietti C, Adamo FM, Ruggeri L, Di Ianni M, Rosati E. Sportoletti P, et al. Among authors: rompietti c. Int J Mol Sci. 2021 Jun 22;22(13):6665. doi: 10.3390/ijms22136665. Int J Mol Sci. 2021. PMID: 34206399 Free PMC article. Review.
Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia.
Guarente V, Martino G, Dorillo E, De Falco F, Rompietti C, Sorcini D, Brogna M, Cardinali V, Ascani S, Marra A, Sportoletti P. Guarente V, et al. Among authors: rompietti c. Front Oncol. 2021 Sep 9;11:729106. doi: 10.3389/fonc.2021.729106. eCollection 2021. Front Oncol. 2021. PMID: 34568060 Free PMC article.
16 results