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SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia.
Bon C, Luffarelli R, Russo R, Fortuni S, Pierattini B, Santulli C, Fimiani C, Persichetti F, Cotella D, Mallamaci A, Santoro C, Carninci P, Espinoza S, Testi R, Zucchelli S, Condò I, Gustincich S. Bon C, et al. Among authors: santoro c. Nucleic Acids Res. 2019 Nov 18;47(20):10728-10743. doi: 10.1093/nar/gkz798. Nucleic Acids Res. 2019. PMID: 31584077 Free PMC article.
SINEUP Non-coding RNA Targeting GDNF Rescues Motor Deficits and Neurodegeneration in a Mouse Model of Parkinson's Disease.
Espinoza S, Scarpato M, Damiani D, Managò F, Mereu M, Contestabile A, Peruzzo O, Carninci P, Santoro C, Papaleo F, Mingozzi F, Ronzitti G, Zucchelli S, Gustincich S. Espinoza S, et al. Among authors: santoro c. Mol Ther. 2020 Feb 5;28(2):642-652. doi: 10.1016/j.ymthe.2019.08.005. Epub 2019 Aug 16. Mol Ther. 2020. PMID: 31495777 Free PMC article.
Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease.
Carrieri C, Forrest AR, Santoro C, Persichetti F, Carninci P, Zucchelli S, Gustincich S. Carrieri C, et al. Among authors: santoro c. Front Cell Neurosci. 2015 Apr 1;9:114. doi: 10.3389/fncel.2015.00114. eCollection 2015. Front Cell Neurosci. 2015. PMID: 25883552 Free PMC article.
SINEUPs: a novel toolbox for RNA therapeutics.
Espinoza S, Bon C, Valentini P, Pierattini B, Matey AT, Damiani D, Pulcrano S, Sanges R, Persichetti F, Takahashi H, Carninci P, Santoro C, Cotella D, Gustincich S. Espinoza S, et al. Among authors: santoro c. Essays Biochem. 2021 Oct 27;65(4):775-789. doi: 10.1042/EBC20200114. Essays Biochem. 2021. PMID: 34623427 Free PMC article. Review.
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases.
Zucchelli S, Fedele S, Vatta P, Calligaris R, Heutink P, Rizzu P, Itoh M, Persichetti F, Santoro C, Kawaji H, Lassmann T, Hayashizaki Y, Carninci P, Forrest ARR; FANTOM Consortium; Gustincich S. Zucchelli S, et al. Among authors: santoro c. Mol Neurobiol. 2019 Aug;56(8):5392-5415. doi: 10.1007/s12035-018-1465-2. Epub 2019 Jan 4. Mol Neurobiol. 2019. PMID: 30610612 Free PMC article.
The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs.
Fasolo F, Patrucco L, Volpe M, Bon C, Peano C, Mignone F, Carninci P, Persichetti F, Santoro C, Zucchelli S, Sblattero D, Sanges R, Cotella D, Gustincich S. Fasolo F, et al. Among authors: santoro c. FASEB J. 2019 Dec;33(12):13572-13589. doi: 10.1096/fj.201901618RR. Epub 2019 Oct 25. FASEB J. 2019. PMID: 31570000 Free PMC article.
Here we show the interactome profile of the mouse inverted short interspersed nuclear element (SINE) of subfamily B2 (invSINEB2) alone and embedded in antisense (AS) ubiquitin C-terminal hydrolase L1 (Uchl1), an lncRNA that is AS to Uchl1 gene. AS Uchl1 is the representati …
Here we show the interactome profile of the mouse inverted short interspersed nuclear element (SINE) of subfamily B2 (invSINEB2) alone and e …
685 results