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A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier.
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, Rodriguez-Rivera FP, Schwaid AG, Malinverni JC, Balibar CJ, Bodea S, Si Q, Wang H, Homsher MF, Painter RE, Ogawa AK, Sutterlin H, Roemer T, Black TA, Rothman DM, Walker SS, Silhavy TJ. Hart EM, et al. Among authors: grabowicz m. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21748-21757. doi: 10.1073/pnas.1912345116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591200 Free PMC article.
Characterization of a stalled complex on the β-barrel assembly machine.
Lee J, Xue M, Wzorek JS, Wu T, Grabowicz M, Gronenberg LS, Sutterlin HA, Davis RM, Ruiz N, Silhavy TJ, Kahne DE. Lee J, et al. Among authors: grabowicz m. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8717-22. doi: 10.1073/pnas.1604100113. Epub 2016 Jul 20. Proc Natl Acad Sci U S A. 2016. PMID: 27439868 Free PMC article.
Envelope Stress Responses: An Interconnected Safety Net.
Grabowicz M, Silhavy TJ. Grabowicz M, et al. Trends Biochem Sci. 2017 Mar;42(3):232-242. doi: 10.1016/j.tibs.2016.10.002. Epub 2016 Nov 8. Trends Biochem Sci. 2017. PMID: 27839654 Free PMC article. Review.
43 results