Lee HW - Search Results

1

Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice.

Tang MS, Wu XR, Lee HW, Xia Y, Deng FM, Moreira AL, Chen LC, Huang WC, Lepor H. Tang MS, et al. Among authors: lee hw. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21727-21731. doi: 10.1073/pnas.1911321116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591243 Free PMC article.

2

E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells.

Lee HW, Park SH, Weng MW, Wang HT, Huang WC, Lepor H, Wu XR, Chen LC, Tang MS. Lee HW, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1560-E1569. doi: 10.1073/pnas.1718185115. Epub 2018 Jan 29. Proc Natl Acad Sci U S A. 2018. PMID: 29378943 Free PMC article.

3

Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis.

Weng MW, Lee HW, Park SH, Hu Y, Wang HT, Chen LC, Rom WN, Huang WC, Lepor H, Wu XR, Yang CS, Tang MS. Weng MW, et al. Among authors: lee hw. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6152-E6161. doi: 10.1073/pnas.1804869115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915082 Free PMC article.

4

DNA damage, DNA repair and carcinogenicity: Tobacco smoke versus electronic cigarette aerosol.

Tang MS, Lee HW, Weng MW, Wang HT, Hu Y, Chen LC, Park SH, Chan HW, Xu J, Wu XR, Wang H, Yang R, Galdane K, Jackson K, Chu A, Halzack E. Tang MS, et al. Among authors: lee hw. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108409. doi: 10.1016/j.mrrev.2021.108409. Epub 2021 Dec 20. Mutat Res Rev Mutat Res. 2022. PMID: 35690412 Free PMC article. Review.

5

Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells.

Lee HW, Wang HT, Weng MW, Hu Y, Chen WS, Chou D, Liu Y, Donin N, Huang WC, Lepor H, Wu XR, Wang H, Beland FA, Tang MS. Lee HW, et al. Oncotarget. 2014 Jun 15;5(11):3526-40. doi: 10.18632/oncotarget.1954. Oncotarget. 2014. PMID: 24939871 Free PMC article.

6

Cigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation.

Lee HW, Wang HT, Weng MW, Chin C, Huang W, Lepor H, Wu XR, Rom WN, Chen LC, Tang MS. Lee HW, et al. Oncotarget. 2015 Oct 20;6(32):33226-36. doi: 10.18632/oncotarget.5429. Oncotarget. 2015. PMID: 26431382 Free PMC article.

7

The role of TAp63γ and P53 point mutations in regulating DNA repair, mutational susceptibility and invasion of bladder cancer cells.

Wang HT, Lee HW, Weng MW, Liu Y, Huang WC, Lepor H, Wu XR, Tang MS. Wang HT, et al. Among authors: lee hw. Elife. 2021 Nov 8;10:e71184. doi: 10.7554/eLife.71184. Elife. 2021. PMID: 34747697 Free PMC article.

8

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249.

Weng MW, Lee HW, Choi B, Wang HT, Hu Y, Mehta M, Desai D, Amin S, Zheng Y, Tang MS. Weng MW, et al. Among authors: lee hw. Oncotarget. 2017 Mar 14;8(11):18213-18226. doi: 10.18632/oncotarget.15313. Oncotarget. 2017. PMID: 28212554 Free PMC article.

9

Impact on rats from acute intratracheal inhalation exposures to WTC dusts.

Cohen MD, Prophete C, Horton L, Sisco M, Park SH, Lee HW, Zelikoff J, Chen LC. Cohen MD, et al. Among authors: lee hw. Inhal Toxicol. 2020 Apr;32(5):218-230. doi: 10.1080/08958378.2020.1768322. Epub 2020 May 25. Inhal Toxicol. 2020. PMID: 32448006

10

Longitudinal impact on rat cardiac tissue transcriptomic profiles due to acute intratracheal inhalation exposures to isoflurane.

Park SH, Lu Y, Shao Y, Prophete C, Horton L, Sisco M, Lee HW, Kluz T, Sun H, Costa M, Zelikoff J, Chen LC, Cohen MD. Park SH, et al. Among authors: lee hw. PLoS One. 2021 Oct 14;16(10):e0257241. doi: 10.1371/journal.pone.0257241. eCollection 2021. PLoS One. 2021. PMID: 34648499 Free PMC article.

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