Lewis CW - Search Results

1

Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition.

Lewis CW, Bukhari AB, Xiao EJ, Choi WS, Smith JD, Homola E, Mackey JR, Campbell SD, Gamper AM, Chan GK. Lewis CW, et al. Cancer Res. 2019 Dec 1;79(23):5971-5985. doi: 10.1158/0008-5472.CAN-19-1961. Epub 2019 Oct 8. Cancer Res. 2019. PMID: 31594837

2

Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism.

Ayoub AT, Abou El-Magd RM, Xiao J, Lewis CW, Tilli TM, Arakawa K, Nindita Y, Chan G, Sun L, Glover M, Klobukowski M, Tuszynski J. Ayoub AT, et al. Among authors: lewis cw. J Med Chem. 2016 Oct 27;59(20):9532-9540. doi: 10.1021/acs.jmedchem.6b01264. Epub 2016 Oct 18. J Med Chem. 2016. PMID: 27718573

3

Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxel.

Lewis CW, Jin Z, Macdonald D, Wei W, Qian XJ, Choi WS, He R, Sun X, Chan G. Lewis CW, et al. Oncotarget. 2017 May 13;8(43):73705-73722. doi: 10.18632/oncotarget.17848. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088738 Free PMC article.

4

Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis.

Bukhari AB, Lewis CW, Pearce JJ, Luong D, Chan GK, Gamper AM. Bukhari AB, et al. Among authors: lewis cw. J Clin Invest. 2019 Mar 1;129(3):1329-1344. doi: 10.1172/JCI122622. Epub 2019 Feb 18. J Clin Invest. 2019. PMID: 30645202 Free PMC article.

5

Automated classification of mitotic catastrophe by use of the centromere fragmentation morphology.

Roy K, Lewis CW, Chan GK, Bhattacharjee D. Roy K, et al. Among authors: lewis cw. Biochem Cell Biol. 2021 Apr;99(2):261-271. doi: 10.1139/bcb-2020-0395. Epub 2020 Sep 9. Biochem Cell Biol. 2021. PMID: 32905704

6

Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives.

Muslimin R, Nishiura N, Teshima A, Do KM, Kodama T, Morita H, Lewis CW, Chan G, Ayoub AT, Arakawa K. Muslimin R, et al. Among authors: lewis cw. Bioorg Med Chem. 2022 Jan 1;53:116551. doi: 10.1016/j.bmc.2021.116551. Epub 2021 Dec 5. Bioorg Med Chem. 2022. PMID: 34883453

7

Bioinspired computational design of lankacidin derivatives for improvement in antitumor activity.

Ayoub AT, Nishiura N, Teshima A, Elrefaiy MA, Muslimin R, Do KM, Kodama T, Lewis CW, Chan G, Morita H, Arakawa K. Ayoub AT, et al. Among authors: lewis cw. Future Med Chem. 2022 Oct;14(19):1349-1360. doi: 10.4155/fmc-2022-0134. Epub 2022 Sep 8. Future Med Chem. 2022. PMID: 36073363

8

Myt1 overexpression mediates resistance to cell cycle and DNA damage checkpoint kinase inhibitors.

Sokhi S, Lewis CW, Bukhari AB, Hadfield J, Xiao EJ, Fung J, Yoon YJ, Hsu WH, Gamper AM, Chan GK. Sokhi S, et al. Among authors: lewis cw. Front Cell Dev Biol. 2023 Nov 2;11:1270542. doi: 10.3389/fcell.2023.1270542. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020882 Free PMC article.

9

Measurement of Cdk1/Cyclin B Kinase Activity by Specific Antibodies and Western Blotting.

Lewis CW, Taylor RG, Golsteyn RM. Lewis CW, et al. Methods Mol Biol. 2016;1342:337-48. doi: 10.1007/978-1-4939-2957-3_21. Methods Mol Biol. 2016. PMID: 26254935

10

A western blot assay to measure cyclin dependent kinase activity in cells or in vitro without the use of radioisotopes.

Lewis CW, Taylor RG, Kubara PM, Marshall K, Meijer L, Golsteyn RM. Lewis CW, et al. FEBS Lett. 2013 Sep 17;587(18):3089-95. doi: 10.1016/j.febslet.2013.08.003. Epub 2013 Aug 15. FEBS Lett. 2013. PMID: 23954627 Free article.

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