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Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly.
Plimpton RL, Cuéllar J, Lai CW, Aoba T, Makaju A, Franklin S, Mathis AD, Prince JT, Carrascosa JL, Valpuesta JM, Willardson BM. Plimpton RL, et al. Among authors: makaju a. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2413-8. doi: 10.1073/pnas.1419595112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675501 Free PMC article.
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.
Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S. Warren JS, et al. Among authors: makaju a. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7871-E7880. doi: 10.1073/pnas.1800680115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061404 Free PMC article.
Molecular architecture of the Bardet-Biedl syndrome protein 2-7-9 subcomplex.
Ludlam WG, Aoba T, Cuéllar J, Bueno-Carrasco MT, Makaju A, Moody JD, Franklin S, Valpuesta JM, Willardson BM. Ludlam WG, et al. Among authors: makaju a. J Biol Chem. 2019 Nov 1;294(44):16385-16399. doi: 10.1074/jbc.RA119.010150. Epub 2019 Sep 17. J Biol Chem. 2019. PMID: 31530639 Free PMC article.
The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.
Sato M, Kadomatsu T, Miyata K, Warren JS, Tian Z, Zhu S, Horiguchi H, Makaju A, Bakhtina A, Morinaga J, Sugizaki T, Hirashima K, Yoshinobu K, Imasaka M, Araki M, Komohara Y, Wakayama T, Nakagawa S, Franklin S, Node K, Araki K, Oike Y. Sato M, et al. Among authors: makaju a. Nat Commun. 2021 May 5;12(1):2529. doi: 10.1038/s41467-021-22735-7. Nat Commun. 2021. PMID: 33953175 Free PMC article.
Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support.
Drakos SG, Badolia R, Makaju A, Kyriakopoulos CP, Wever-Pinzon O, Tracy CM, Bakhtina A, Bia R, Parnell T, Taleb I, Ramadurai DKA, Navankasattusas S, Dranow E, Hanff TC, Tseliou E, Shankar TS, Visker J, Hamouche R, Stauder EL, Caine WT, Alharethi R, Selzman CH, Franklin S. Drakos SG, et al. Among authors: makaju a. Circulation. 2023 Jan 31;147(5):409-424. doi: 10.1161/CIRCULATIONAHA.121.056600. Epub 2022 Nov 30. Circulation. 2023. PMID: 36448446 Free PMC article.
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