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Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus.
de Groot A, Siponen MI, Magerand R, Eugénie N, Martin-Arevalillo R, Doloy J, Lemaire D, Brandelet G, Parcy F, Dumas R, Roche P, Servant P, Confalonieri F, Arnoux P, Pignol D, Blanchard L. de Groot A, et al. Among authors: roche p. Nucleic Acids Res. 2019 Dec 2;47(21):11403-11417. doi: 10.1093/nar/gkz883. Nucleic Acids Res. 2019. PMID: 31598697 Free PMC article.
ChemoDOTS: a web server to design chemistry-driven focused libraries.
Hoffer L, Charifi-Hoareau G, Barelier S, Betzi S, Miller T, Morelli X, Roche P. Hoffer L, et al. Among authors: roche p. Nucleic Acids Res. 2024 Jul 5;52(W1):W461-W468. doi: 10.1093/nar/gkae326. Nucleic Acids Res. 2024. PMID: 38686808 Free PMC article.
TM0486 from the hyperthermophilic anaerobe Thermotoga maritima is a thiamin-binding protein involved in response of the cell to oxidative conditions.
Dermoun Z, Foulon A, Miller MD, Harrington DJ, Deacon AM, Sebban-Kreuzer C, Roche P, Lafitte D, Bornet O, Wilson IA, Dolla A. Dermoun Z, et al. Among authors: roche p. J Mol Biol. 2010 Jul 16;400(3):463-76. doi: 10.1016/j.jmb.2010.05.014. Epub 2010 May 13. J Mol Biol. 2010. PMID: 20471400 Free PMC article.
Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins.
Raux B, Voitovich Y, Derviaux C, Lugari A, Rebuffet E, Milhas S, Priet S, Roux T, Trinquet E, Guillemot JC, Knapp S, Brunel JM, Fedorov AY, Collette Y, Roche P, Betzi S, Combes S, Morelli X. Raux B, et al. Among authors: roche p. J Med Chem. 2016 Feb 25;59(4):1634-41. doi: 10.1021/acs.jmedchem.5b01708. Epub 2016 Jan 6. J Med Chem. 2016. PMID: 26735842
CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.
Carrasco K, Montersino C, Derviaux C, Saez-Ayala M, Hoffer L, Restouin A, Castellano R, Casassa J, Roche P, Pasquier E, Combes S, Morelli X, Collette Y, Betzi S. Carrasco K, et al. Among authors: roche p. J Med Chem. 2022 Apr 14;65(7):5660-5674. doi: 10.1021/acs.jmedchem.1c02168. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35348328 Free article.
A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays.
Guiseppi A, Vicente JJ, Herrou J, Byrne D, Barneoud A, Moine A, Espinosa L, Basse MJ, Molle V, Mignot T, Roche P, Mauriello EMF. Guiseppi A, et al. Among authors: roche p. PLoS Genet. 2019 Dec 20;15(12):e1008533. doi: 10.1371/journal.pgen.1008533. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31860666 Free PMC article.
894 results