Fiehn O - Search Results

1

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.

Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. Cai D, et al. Among authors: fiehn o. Nat Commun. 2019 Oct 11;10(1):4621. doi: 10.1038/s41467-019-12529-3. Nat Commun. 2019. PMID: 31604910 Free PMC article.

2

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.

Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. Wang J, et al. Among authors: fiehn o. Cancer Lett. 2016 Aug 10;378(2):69-79. doi: 10.1016/j.canlet.2016.05.004. Epub 2016 May 6. Cancer Lett. 2016. PMID: 27164560 Free PMC article.

3

Tracking Polymicrobial Metabolism in Cystic Fibrosis Airways: Pseudomonas aeruginosa Metabolism and Physiology Are Influenced by Rothia mucilaginosa-Derived Metabolites.

Gao B, Gallagher T, Zhang Y, Elbadawi-Sidhu M, Lai Z, Fiehn O, Whiteson KL. Gao B, et al. Among authors: fiehn o. mSphere. 2018 Apr 25;3(2):e00151-18. doi: 10.1128/mSphere.00151-18. Print 2018 Apr 25. mSphere. 2018. PMID: 29695623 Free PMC article.

4

Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma.

Gao B, Lue HW, Podolak J, Fan S, Zhang Y, Serawat A, Alumkal JJ, Fiehn O, Thomas GV. Gao B, et al. Among authors: fiehn o. Metabolites. 2019 Apr 26;9(5):82. doi: 10.3390/metabo9050082. Metabolites. 2019. PMID: 31035489 Free PMC article.

5

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.

Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženović I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E. Eckert MA, et al. Among authors: fiehn o. Nature. 2019 May;569(7758):723-728. doi: 10.1038/s41586-019-1173-8. Epub 2019 May 1. Nature. 2019. PMID: 31043742 Free PMC article.

6

Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway.

Xia Y, Ye B, Ding J, Yu Y, Alptekin A, Thangaraju M, Prasad PD, Ding ZC, Park EJ, Choi JH, Gao B, Fiehn O, Yan C, Dong Z, Zha Y, Ding HF. Xia Y, et al. Among authors: fiehn o. Cancer Res. 2019 Aug 1;79(15):3837-3850. doi: 10.1158/0008-5472.CAN-18-3541. Epub 2019 May 14. Cancer Res. 2019. PMID: 31088832 Free PMC article.

7

Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining.

Barupal DK, Gao B, Budczies J, Phinney BS, Perroud B, Denkert C, Fiehn O. Barupal DK, et al. Among authors: fiehn o. Oncotarget. 2019 Jun 11;10(39):3894-3909. doi: 10.18632/oncotarget.26995. eCollection 2019 Jun 11. Oncotarget. 2019. PMID: 31231467 Free PMC article.

8

Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy.

Ma Z, Li J, Lin K, Ramachandran M, Zhang D, Showalter M, De Souza C, Lindstrom A, Solano LN, Jia B, Urayama S, Duan Y, Fiehn O, Lin TY, Li M, Li Y. Ma Z, et al. Among authors: fiehn o. Nat Commun. 2020 Sep 15;11(1):4615. doi: 10.1038/s41467-020-18399-4. Nat Commun. 2020. PMID: 32934241 Free PMC article.

9

Comparing Stable Isotope Enrichment by Gas Chromatography with Time-of-Flight, Quadrupole Time-of-Flight, and Quadrupole Mass Spectrometry.

Zhang Y, Gao B, Valdiviez L, Zhu C, Gallagher T, Whiteson K, Fiehn O. Zhang Y, et al. Among authors: fiehn o. Anal Chem. 2021 Feb 2;93(4):2174-2182. doi: 10.1021/acs.analchem.0c04013. Epub 2021 Jan 12. Anal Chem. 2021. PMID: 33434014 Free PMC article.

10

Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice.

Zhou R, Llorente C, Cao J, Zaramela LS, Zeng S, Gao B, Li SZ, Welch RD, Huang FQ, Qi LW, Pan C, Huang Y, Zhou P, Beussen I, Zhang Y, Bryam G, Fiehn O, Wang L, Liu EH, Yu RT, Downes M, Evans RM, Goglin K, Fouts DE, Brenner DA, Bode L, Fan X, Zengler K, Schnabl B. Zhou R, et al. Among authors: fiehn o. Cell Mol Gastroenterol Hepatol. 2021;12(1):293-320. doi: 10.1016/j.jcmgh.2021.02.009. Epub 2021 Feb 22. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33631374 Free PMC article.

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