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RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.
Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. Cai D, et al. Among authors: zou h, zou jx. Nat Commun. 2019 Oct 11;10(1):4621. doi: 10.1038/s41467-019-12529-3. Nat Commun. 2019. PMID: 31604910 Free PMC article.
Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin.
Zheng J, Wang J, Wang Q, Zou H, Wang H, Zhang Z, Chen J, Wang Q, Wang P, Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, Chen HW, Liu P, Liu Y, Han F, Wang J. Zheng J, et al. Among authors: zou h. Acta Pharm Sin B. 2020 Dec;10(12):2313-2322. doi: 10.1016/j.apsb.2020.07.001. Epub 2020 Jul 12. Acta Pharm Sin B. 2020. PMID: 33354503 Free PMC article.
Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.
Zheng J, Wang Q, Chen J, Cai G, Zhang Z, Zou H, Zou JX, Liu Q, Ji S, Shao G, Li H, Li S, Chen HW, Lu L, Yuan Y, Liu P, Wang J. Zheng J, et al. Among authors: zou h, zou jx. Cell Rep Med. 2024 May 21;5(5):101519. doi: 10.1016/j.xcrm.2024.101519. Epub 2024 Apr 30. Cell Rep Med. 2024. PMID: 38692271 Free PMC article.
5,674 results