Scott DJ - Search Results

1

Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase.

Cain R, Salimraj R, Punekar AS, Bellini D, Fishwick CWG, Czaplewski L, Scott DJ, Harris G, Dowson CG, Lloyd AJ, Roper DI. Cain R, et al. Among authors: scott dj. J Med Chem. 2019 Nov 14;62(21):9703-9717. doi: 10.1021/acs.jmedchem.9b01131. Epub 2019 Nov 5. J Med Chem. 2019. PMID: 31626547 Free article.

2

Expression, purification and crystallization of the cell-division protein YgfE from Escherichia coli.

Addinall SG, Johnson KA, Dafforn T, Smith C, Rodger A, Gomez RP, Sloan K, Blewett A, Scott DJ, Roper DI. Addinall SG, et al. Among authors: scott dj. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt 3):305-7. doi: 10.1107/S1744309105003945. Epub 2005 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16511026 Free PMC article.

3

Structural characterisation of the insecticidal toxin XptA1, reveals a 1.15 MDa tetramer with a cage-like structure.

Lee SC, Stoilova-McPhie S, Baxter L, Fülöp V, Henderson J, Rodger A, Roper DI, Scott DJ, Smith CJ, Morgan JA. Lee SC, et al. Among authors: scott dj. J Mol Biol. 2007 Mar 9;366(5):1558-68. doi: 10.1016/j.jmb.2006.12.057. Epub 2006 Dec 23. J Mol Biol. 2007. PMID: 17266984

4

FtsZ polymer-bundling by the Escherichia coli ZapA orthologue, YgfE, involves a conformational change in bound GTP.

Small E, Marrington R, Rodger A, Scott DJ, Sloan K, Roper D, Dafforn TR, Addinall SG. Small E, et al. Among authors: scott dj. J Mol Biol. 2007 May 25;369(1):210-21. doi: 10.1016/j.jmb.2007.03.025. Epub 2007 Mar 19. J Mol Biol. 2007. PMID: 17428494

5

The Vip3Ag4 Insecticidal Protoxin from Bacillus thuringiensis Adopts A Tetrameric Configuration That Is Maintained on Proteolysis.

Palma L, Scott DJ, Harris G, Din SU, Williams TL, Roberts OJ, Young MT, Caballero P, Berry C. Palma L, et al. Among authors: scott dj. Toxins (Basel). 2017 May 14;9(5):165. doi: 10.3390/toxins9050165. Toxins (Basel). 2017. PMID: 28505109 Free PMC article.

6

Structural modeling of an outer membrane electron conduit from a metal-reducing bacterium suggests electron transfer via periplasmic redox partners.

Edwards MJ, White GF, Lockwood CW, Lawes MC, Martel A, Harris G, Scott DJ, Richardson DJ, Butt JN, Clarke TA. Edwards MJ, et al. Among authors: scott dj. J Biol Chem. 2018 May 25;293(21):8103-8112. doi: 10.1074/jbc.RA118.001850. Epub 2018 Apr 10. J Biol Chem. 2018. PMID: 29636412 Free PMC article.

7

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization.

Punekar AS, Samsudin F, Lloyd AJ, Dowson CG, Scott DJ, Khalid S, Roper DI. Punekar AS, et al. Among authors: scott dj. Cell Surf. 2018 Jun;2:54-66. doi: 10.1016/j.tcsw.2018.06.002. Cell Surf. 2018. PMID: 30046666 Free PMC article.

8

The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases.

Pander B, Harris G, Scott DJ, Winzer K, Köpke M, Simpson SD, Minton NP, Henstra AM. Pander B, et al. Among authors: scott dj. Appl Microbiol Biotechnol. 2019 Sep;103(17):7275-7286. doi: 10.1007/s00253-019-10015-w. Epub 2019 Jul 25. Appl Microbiol Biotechnol. 2019. PMID: 31346685 Free PMC article.

9

Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.

Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.

10

Allosteric inhibition of human exonuclease1 (hExo1) through a novel extended β-sheet conformation.

Umar AA, Liddell S, Hussain R, Siligardi G, Harris G, Carr S, Asiani K, Gowers DM, Odell M, Scott DJ. Umar AA, et al. Among authors: scott dj. Biochim Biophys Acta Gen Subj. 2020 Dec;1864(12):129730. doi: 10.1016/j.bbagen.2020.129730. Epub 2020 Sep 12. Biochim Biophys Acta Gen Subj. 2020. PMID: 32926959

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