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262 results

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Page 1
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods.
McMullen PD, Bhattacharya S, Woods CG, Pendse SN, McBride MT, Soldatow VY, Deisenroth C, LeCluyse EL, Clewell RA, Andersen ME. McMullen PD, et al. Among authors: woods cg. Toxicol In Vitro. 2020 Apr;64:104463. doi: 10.1016/j.tiv.2019.02.017. Epub 2019 Oct 15. Toxicol In Vitro. 2020. PMID: 31628012 Free article.
A map of the PPARα transcription regulatory network for primary human hepatocytes.
McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. McMullen PD, et al. Among authors: woods cg. Chem Biol Interact. 2014 Feb 25;209:14-24. doi: 10.1016/j.cbi.2013.11.006. Epub 2013 Nov 22. Chem Biol Interact. 2014. PMID: 24269660 Free article.
A systems biology perspective on Nrf2-mediated antioxidant response.
Zhang Q, Pi J, Woods CG, Andersen ME. Zhang Q, et al. Among authors: woods cg. Toxicol Appl Pharmacol. 2010 Apr 1;244(1):84-97. doi: 10.1016/j.taap.2009.08.018. Epub 2009 Aug 28. Toxicol Appl Pharmacol. 2010. PMID: 19716833 Free PMC article. Review.
Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches.
Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Bhattacharya S, et al. Among authors: woods cg. Front Physiol. 2012 Dec 14;3:462. doi: 10.3389/fphys.2012.00462. eCollection 2012. Front Physiol. 2012. PMID: 23248599 Free PMC article.
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Godoy P, et al. Among authors: woods cg. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Arch Toxicol. 2013. PMID: 23974980 Free PMC article. Review.
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.
Pi J, Zhang Q, Fu J, Woods CG, Hou Y, Corkey BE, Collins S, Andersen ME. Pi J, et al. Among authors: woods cg. Toxicol Appl Pharmacol. 2010 Apr 1;244(1):77-83. doi: 10.1016/j.taap.2009.05.025. Epub 2009 Jun 6. Toxicol Appl Pharmacol. 2010. PMID: 19501608 Free PMC article. Review.
Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response.
Xue P, Hou Y, Zhang Q, Woods CG, Yarborough K, Liu H, Sun G, Andersen ME, Pi J. Xue P, et al. Among authors: woods cg. Biochem Biophys Res Commun. 2011 Apr 8;407(2):360-5. doi: 10.1016/j.bbrc.2011.03.024. Epub 2011 Mar 17. Biochem Biophys Res Commun. 2011. PMID: 21396911 Free PMC article.
Hormesis and adaptive cellular control systems.
Zhang Q, Pi J, Woods CG, Jarabek AM, Clewell HJ 3rd, Andersen ME. Zhang Q, et al. Among authors: woods cg. Dose Response. 2008 Mar 19;6(2):196-208. doi: 10.2203/dose-response.07-028.Zhang. Dose Response. 2008. PMID: 18648578 Free PMC article.
262 results