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Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
Taskar KS, Pilla Reddy V, Burt H, Posada MM, Varma M, Zheng M, Ullah M, Emami Riedmaier A, Umehara KI, Snoeys J, Nakakariya M, Chu X, Beneton M, Chen Y, Huth F, Narayanan R, Mukherjee D, Dixit V, Sugiyama Y, Neuhoff S. Taskar KS, et al. Among authors: dixit v. Clin Pharmacol Ther. 2020 May;107(5):1082-1115. doi: 10.1002/cpt.1693. Epub 2019 Dec 31. Clin Pharmacol Ther. 2020. PMID: 31628859 Free PMC article. Review.
Physiologically-Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective.
Heimbach T, Chen Y, Chen J, Dixit V, Parrott N, Peters SA, Poggesi I, Sharma P, Snoeys J, Shebley M, Tai G, Tse S, Upreti VV, Wang YH, Tsai A, Xia B, Zheng M, Zhu AZX, Hall S. Heimbach T, et al. Among authors: dixit v. Clin Pharmacol Ther. 2021 Aug;110(2):297-310. doi: 10.1002/cpt.2125. Epub 2020 Dec 30. Clin Pharmacol Ther. 2021. PMID: 33270249 Free PMC article.
Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture.
Pourmal S, Truong ME, Johnson MC, Yang Y, Zhou L, Alegre K, Stowe IB, Gupta S, Chen PA, Zhang Y, Rohou A, Newton K, Kayagaki N, Dixit VM, Deshpande I. Pourmal S, et al. Among authors: dixit vm. Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08273-4. Online ahead of print. Nature. 2024. PMID: 39476863
Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation.
Gonzalez-Hurtado E, Leveau C, Li K, Qu R, Mishra M, Goldberg EL, Sidorov S, Yeung ST, Khairallah C, Gonzalez D, Shepard TM, Camell C, Artyomov MN, Kluger Y, Khanna KM, Dixit VD. Gonzalez-Hurtado E, et al. Among authors: dixit vd. bioRxiv [Preprint]. 2024 Oct 13:2024.10.12.618004. doi: 10.1101/2024.10.12.618004. bioRxiv. 2024. PMID: 39416197 Free PMC article. Preprint.
Cysteine depletion triggers adipose tissue thermogenesis and weight-loss.
Lee AH, Orliaguet L, Youm YH, Maeda R, Dlugos T, Lei Y, Coman D, Shchukina I, Andhey S, Smith SR, Ravussin E, Stadler K, Hyder F, Artyomov MN, Sugiura Y, Dixit VD. Lee AH, et al. Among authors: dixit vd. bioRxiv [Preprint]. 2024 Aug 8:2024.08.06.606880. doi: 10.1101/2024.08.06.606880. bioRxiv. 2024. PMID: 39149397 Free PMC article. Preprint.
Feedback based gas sensing setup for ppb to ppm level sensing.
Tom A, Singh DK, Shaw VK, Abhijith PV, Sajana S, Kirandas PS, Dixit V, Kamble V, Pai SP, Jaiswal-Nagar D. Tom A, et al. Among authors: dixit v. Rev Sci Instrum. 2024 Aug 1;95(8):085003. doi: 10.1063/5.0202940. Rev Sci Instrum. 2024. PMID: 39145696
1,085 results