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Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.
Chembiochem. 2020 Apr 1;21(7):1028-1035. doi: 10.1002/cbic.201900505. Epub 2019 Dec 19.
Chembiochem. 2020.
PMID: 31633265
Free PMC article.
Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.
Kvach MV, Barzak FM, Harjes S, Schares HAM, Jameson GB, Ayoub AM, Moorthy R, Aihara H, Harris RS, Filichev VV, Harki DA, Harjes E.
Kvach MV, et al. Among authors: schares ham.
Biochemistry. 2019 Feb 5;58(5):391-400. doi: 10.1021/acs.biochem.8b00858. Epub 2018 Nov 28.
Biochemistry. 2019.
PMID: 30418757
Free PMC article.
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Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity.
Jackson PA, Schares HAM, Jones KFM, Widen JC, Dempe DP, Grillet F, Cuellar ME, Walters MA, Harki DA, Brummond KM.
Jackson PA, et al. Among authors: schares ham.
J Med Chem. 2020 Dec 10;63(23):14951-14978. doi: 10.1021/acs.jmedchem.0c01464. Epub 2020 Nov 17.
J Med Chem. 2020.
PMID: 33201697
Free PMC article.
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Function-Oriented and Modular (+/-)-cis-Pseudoguaianolide Synthesis: Discovery of New Nrf2 Activators and NF-κB Inhibitors.
Emmetiere F, Ratnayake R, Schares HAM, Jones KFM, Bevan-Smith E, Luesch H, Harki DA, Grenning AJ.
Emmetiere F, et al. Among authors: schares ham.
Chemistry. 2021 Mar 22;27(17):5564-5571. doi: 10.1002/chem.202100038. Epub 2021 Feb 26.
Chemistry. 2021.
PMID: 33502811
Free PMC article.
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