Hwang SH - Search Results

1

COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.

Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX. Zhang CY, et al. Among authors: hwang sh. FEBS J. 2020 Apr;287(8):1666-1680. doi: 10.1111/febs.15105. Epub 2019 Nov 8. FEBS J. 2020. PMID: 31646730 Free PMC article.

2

Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors.

Hwang SH, Morisseau C, Do Z, Hammock BD. Hwang SH, et al. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5773-7. doi: 10.1016/j.bmcl.2006.08.078. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16949285 Free PMC article.

3

Orally bioavailable potent soluble epoxide hydrolase inhibitors.

Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Hwang SH, et al. J Med Chem. 2007 Aug 9;50(16):3825-40. doi: 10.1021/jm070270t. Epub 2007 Jul 6. J Med Chem. 2007. PMID: 17616115 Free PMC article.

4

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation.

Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. Liu JY, et al. Among authors: hwang sh. Br J Pharmacol. 2009 Jan;156(2):284-96. doi: 10.1111/j.1476-5381.2008.00009.x. Epub 2009 Jan 13. Br J Pharmacol. 2009. PMID: 19154430 Free PMC article.

5

Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo.

Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH. Liu JY, et al. Among authors: hwang sh. Mol Cancer Ther. 2009 Aug;8(8):2193-203. doi: 10.1158/1535-7163.MCT-09-0119. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671760 Free PMC article.

6

Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches.

Li N, Liu JY, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. Li N, et al. Among authors: hwang sh. J Mol Cell Cardiol. 2009 Dec;47(6):835-45. doi: 10.1016/j.yjmcc.2009.08.017. Epub 2009 Aug 28. J Mol Cell Cardiol. 2009. PMID: 19716829 Free PMC article.

7

Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury.

Chaudhary KR, Abukhashim M, Hwang SH, Hammock BD, Seubert JM. Chaudhary KR, et al. Among authors: hwang sh. J Cardiovasc Pharmacol. 2010 Jan;55(1):67-73. doi: 10.1097/FJC.0b013e3181c37d69. J Cardiovasc Pharmacol. 2010. PMID: 19834332 Free PMC article.

8

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.

Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Liu JY, et al. Among authors: hwang sh. Biochem Pharmacol. 2010 Mar 15;79(6):880-7. doi: 10.1016/j.bcp.2009.10.025. Epub 2009 Nov 5. Biochem Pharmacol. 2010. PMID: 19896470 Free PMC article.

9

Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs.

Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD. Tsai HJ, et al. Among authors: hwang sh. Eur J Pharm Sci. 2010 Jun 14;40(3):222-38. doi: 10.1016/j.ejps.2010.03.018. Epub 2010 Mar 30. Eur J Pharm Sci. 2010. PMID: 20359531 Free PMC article.

10

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH. Luo P, et al. Among authors: hwang sh. J Pharmacol Exp Ther. 2010 Aug;334(2):430-8. doi: 10.1124/jpet.110.167544. Epub 2010 May 3. J Pharmacol Exp Ther. 2010. PMID: 20439437 Free PMC article.

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