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Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
McGowan DC, Balemans W, Embrechts W, Motte M, Keown JR, Buyck C, Corbera J, Funes M, Moreno L, Cooymans L, Tahri A, Eymard J, Stoops B, Strijbos R, Van den Berg J, Fodor E, Grimes JM, Koul A, Jonckers THM, Raboisson P, Guillemont J. McGowan DC, et al. Among authors: grimes jm. J Med Chem. 2019 Nov 14;62(21):9680-9690. doi: 10.1021/acs.jmedchem.9b01091. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31647875 Free PMC article.
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Hengrung N, El Omari K, Serna Martin I, Vreede FT, Cusack S, Rambo RP, Vonrhein C, Bricogne G, Stuart DI, Grimes JM, Fodor E. Hengrung N, et al. Among authors: grimes jm. Nature. 2015 Nov 5;527(7576):114-7. doi: 10.1038/nature15525. Epub 2015 Oct 26. Nature. 2015. PMID: 26503046 Free PMC article.
A Mechanism for the Activation of the Influenza Virus Transcriptase.
Serna Martin I, Hengrung N, Renner M, Sharps J, Martínez-Alonso M, Masiulis S, Grimes JM, Fodor E. Serna Martin I, et al. Among authors: grimes jm. Mol Cell. 2018 Jun 21;70(6):1101-1110.e4. doi: 10.1016/j.molcel.2018.05.011. Epub 2018 Jun 14. Mol Cell. 2018. PMID: 29910112 Free PMC article.
Host ANP32A mediates the assembly of the influenza virus replicase.
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM. Carrique L, et al. Among authors: grimes jm. Nature. 2020 Nov;587(7835):638-643. doi: 10.1038/s41586-020-2927-z. Epub 2020 Nov 18. Nature. 2020. PMID: 33208942 Free PMC article.
Structure of an H3N2 influenza virus nucleoprotein.
Knight ML, Fan H, Bauer DLV, Grimes JM, Fodor E, Keown JR. Knight ML, et al. Among authors: grimes jm. Acta Crystallogr F Struct Biol Commun. 2021 Jul 1;77(Pt 7):208-214. doi: 10.1107/S2053230X2100635X. Epub 2021 Jun 29. Acta Crystallogr F Struct Biol Commun. 2021. PMID: 34196611 Free PMC article.
196 results