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The striatal-enriched protein Rhes is a critical modulator of cocaine-induced molecular and behavioral responses.
Napolitano F, De Rosa A, Russo R, Di Maio A, Garofalo M, Federici M, Migliarini S, Ledonne A, Rizzo FR, Avallone L, Nuzzo T, Biagini T, Pasqualetti M, Mercuri NB, Mazza T, Chambery A, Usiello A. Napolitano F, et al. Among authors: nuzzo t. Sci Rep. 2019 Oct 25;9(1):15294. doi: 10.1038/s41598-019-51839-w. Sci Rep. 2019. PMID: 31653935 Free PMC article.
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.
Punzo D, Errico F, Cristino L, Sacchi S, Keller S, Belardo C, Luongo L, Nuzzo T, Imperatore R, Florio E, De Novellis V, Affinito O, Migliarini S, Maddaloni G, Sisalli MJ, Pasqualetti M, Pollegioni L, Maione S, Chiariotti L, Usiello A. Punzo D, et al. Among authors: nuzzo t. J Neurosci. 2016 Mar 9;36(10):3064-78. doi: 10.1523/JNEUROSCI.3881-15.2016. J Neurosci. 2016. PMID: 26961959 Free PMC article.
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity.
Sacchi S, Novellis V, Paolone G, Nuzzo T, Iannotta M, Belardo C, Squillace M, Bolognesi P, Rosini E, Motta Z, Frassineti M, Bertolino A, Pollegioni L, Morari M, Maione S, Errico F, Usiello A. Sacchi S, et al. Among authors: nuzzo t. Sci Rep. 2017 Apr 10;7:46288. doi: 10.1038/srep46288. Sci Rep. 2017. PMID: 28393897 Free PMC article.
Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients.
Nuzzo T, Sacchi S, Errico F, Keller S, Palumbo O, Florio E, Punzo D, Napolitano F, Copetti M, Carella M, Chiariotti L, Bertolino A, Pollegioni L, Usiello A. Nuzzo T, et al. NPJ Schizophr. 2017 Apr 6;3:16. doi: 10.1038/s41537-017-0015-7. eCollection 2017. NPJ Schizophr. 2017. PMID: 28560262 Free PMC article.
Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D'Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, Canu N, Usiello A. Nuzzo T, et al. Exp Neurol. 2019 Jul;317:51-65. doi: 10.1016/j.expneurol.2019.02.014. Epub 2019 Feb 26. Exp Neurol. 2019. PMID: 30822420
The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients.
Nuzzo T, Punzo D, Devoto P, Rosini E, Paciotti S, Sacchi S, Li Q, Thiolat ML, Véga C, Carella M, Carta M, Gardoni F, Calabresi P, Pollegioni L, Bezard E, Parnetti L, Errico F, Usiello A. Nuzzo T, et al. Sci Rep. 2019 Jun 20;9(1):8898. doi: 10.1038/s41598-019-45419-1. Sci Rep. 2019. PMID: 31222058 Free PMC article.
Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of D-serine within the mouse cerebellum.
Cuomo M, Keller S, Punzo D, Nuzzo T, Affinito O, Coretti L, Carella M, de Rosa V, Florio E, Boscia F, Avvedimento VE, Cocozza S, Errico F, Usiello A, Chiariotti L. Cuomo M, et al. Among authors: nuzzo t. Clin Epigenetics. 2019 Oct 28;11(1):149. doi: 10.1186/s13148-019-0732-z. Clin Epigenetics. 2019. PMID: 31661019 Free PMC article.
Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure.
Palese F, Bonomi E, Nuzzo T, Benussi A, Mellone M, Zianni E, Cisani F, Casamassa A, Alberici A, Scheggia D, Padovani A, Marcello E, Di Luca M, Pittaluga A, Usiello A, Borroni B, Gardoni F. Palese F, et al. Among authors: nuzzo t. Neurobiol Aging. 2020 Feb;86:143-155. doi: 10.1016/j.neurobiolaging.2019.10.015. Epub 2019 Nov 1. Neurobiol Aging. 2020. PMID: 31784278 Free article.
33 results