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519 results

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Page 1
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1.
Villalba M, Redin E, Exposito F, Pajares MJ, Sainz C, Hervas D, Guruceaga E, Diaz-Lagares A, Cirauqui C, Redrado M, Valencia K, de Andrea C, Jantus-Lewintre E, Camps C, Lopez-Lopez R, Lahoz A, Montuenga L, Pio R, Sandoval J, Calvo A. Villalba M, et al. Sci Rep. 2019 Oct 28;9(1):15400. doi: 10.1038/s41598-019-51066-3. Sci Rep. 2019. PMID: 31659178 Free PMC article.
Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients.
Villalba M, Diaz-Lagares A, Redrado M, de Aberasturi AL, Segura V, Bodegas ME, Pajares MJ, Pio R, Freire J, Gomez-Roman J, Montuenga LM, Esteller M, Sandoval J, Calvo A. Villalba M, et al. Oncotarget. 2016 Apr 19;7(16):22752-69. doi: 10.18632/oncotarget.8045. Oncotarget. 2016. PMID: 26989022 Free PMC article.
Development of biological tools to assess the role of TMPRSS4 and identification of novel tumor types with high expression of this prometastatic protein.
Villalba M, Lopez L, Redrado M, Ruiz T, de Aberasturi AL, de la Roja N, Garcia D, Exposito F, de Andrea C, Alvarez-Fernandez E, Montuenga L, Rueda P, Rodriguez MJ, Calvo A. Villalba M, et al. Histol Histopathol. 2017 Sep;32(9):929-940. doi: 10.14670/HH-11-857. Epub 2016 Dec 20. Histol Histopathol. 2017. PMID: 27995596
Translating cancer epigenomics into the clinic: focus on lung cancer.
Mari-Alexandre J, Diaz-Lagares A, Villalba M, Juan O, Crujeiras AB, Calvo A, Sandoval J. Mari-Alexandre J, et al. Among authors: villalba m. Transl Res. 2017 Nov;189:76-92. doi: 10.1016/j.trsl.2017.05.008. Epub 2017 Jun 2. Transl Res. 2017. PMID: 28644958 Review.
miR-146a targets c-met and abolishes colorectal cancer liver metastasis.
Bleau AM, Redrado M, Nistal-Villan E, Villalba M, Exposito F, Redin E, de Aberasturi AL, Larzabal L, Freire J, Gomez-Roman J, Calvo A. Bleau AM, et al. Among authors: villalba m. Cancer Lett. 2018 Feb 1;414:257-267. doi: 10.1016/j.canlet.2017.11.008. Epub 2017 Nov 11. Cancer Lett. 2018. PMID: 29133238
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation.
Redin E, Garmendia I, Lozano T, Serrano D, Senent Y, Redrado M, Villalba M, De Andrea CE, Exposito F, Ajona D, Ortiz-Espinosa S, Remirez A, Bertolo C, Sainz C, Garcia-Pedrero J, Pio R, Lasarte J, Agorreta J, Montuenga LM, Calvo A. Redin E, et al. Among authors: villalba m. J Immunother Cancer. 2021 Mar;9(3):e001496. doi: 10.1136/jitc-2020-001496. J Immunother Cancer. 2021. PMID: 33658304 Free PMC article.
Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer.
Palanca-Ballester C, Hervas D, Villalba M, Valdes-Sanchez T, Garcia D, Alcoriza-Balaguer MI, Benet M, Martinez-Tomas R, Briones-Gomez A, Galbis-Caravajal J, Calvo A, Juan O, Lahoz A, Cases E, Sandoval J. Palanca-Ballester C, et al. Among authors: villalba m. Clin Epigenetics. 2022 Sep 19;14(1):116. doi: 10.1186/s13148-022-01334-3. Clin Epigenetics. 2022. PMID: 36123616 Free PMC article.
519 results