Papa FR - Search Results

1

Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival.

Moore PC, Qi JY, Thamsen M, Ghosh R, Peng J, Gliedt MJ, Meza-Acevedo R, Warren RE, Hiniker A, Kim GE, Maly DJ, Backes BJ, Papa FR, Oakes SA. Moore PC, et al. Among authors: papa fr. Cancer Res. 2019 Dec 15;79(24):6190-6203. doi: 10.1158/0008-5472.CAN-19-1116. Epub 2019 Oct 31. Cancer Res. 2019. PMID: 31672843 Free PMC article.

2

Intracellular signaling by the unfolded protein response.

Bernales S, Papa FR, Walter P. Bernales S, et al. Among authors: papa fr. Annu Rev Cell Dev Biol. 2006;22:487-508. doi: 10.1146/annurev.cellbio.21.122303.120200. Annu Rev Cell Dev Biol. 2006. PMID: 16822172 Review.

3

A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress.

Han D, Upton JP, Hagen A, Callahan J, Oakes SA, Papa FR. Han D, et al. Among authors: papa fr. Biochem Biophys Res Commun. 2008 Jan 25;365(4):777-83. doi: 10.1016/j.bbrc.2007.11.040. Epub 2007 Nov 21. Biochem Biophys Res Commun. 2008. PMID: 18035051

4

Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress.

Upton JP, Austgen K, Nishino M, Coakley KM, Hagen A, Han D, Papa FR, Oakes SA. Upton JP, et al. Among authors: papa fr. Mol Cell Biol. 2008 Jun;28(12):3943-51. doi: 10.1128/MCB.00013-08. Epub 2008 Apr 21. Mol Cell Biol. 2008. PMID: 18426910 Free PMC article.

5

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR. Han D, et al. Among authors: papa fr. Cell. 2009 Aug 7;138(3):562-75. doi: 10.1016/j.cell.2009.07.017. Cell. 2009. PMID: 19665977 Free PMC article.

6

Signaling cell death from the endoplasmic reticulum stress response.

Shore GC, Papa FR, Oakes SA. Shore GC, et al. Among authors: papa fr. Curr Opin Cell Biol. 2011 Apr;23(2):143-9. doi: 10.1016/j.ceb.2010.11.003. Epub 2010 Dec 9. Curr Opin Cell Biol. 2011. PMID: 21146390 Free PMC article. Review.

7

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR. Lerner AG, et al. Among authors: papa fr. Cell Metab. 2012 Aug 8;16(2):250-64. doi: 10.1016/j.cmet.2012.07.007. Cell Metab. 2012. PMID: 22883233 Free PMC article.

8

Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.

Papa FR. Papa FR. Cold Spring Harb Perspect Med. 2012 Sep 1;2(9):a007666. doi: 10.1101/cshperspect.a007666. Cold Spring Harb Perspect Med. 2012. PMID: 22951443 Free PMC article. Review.

9

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA. Upton JP, et al. Among authors: papa fr. Science. 2012 Nov 9;338(6108):818-22. doi: 10.1126/science.1226191. Epub 2012 Oct 4. Science. 2012. PMID: 23042294 Free PMC article.

10

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors.

Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, Schürer SC, Oakes SA, Papa FR, Maly DJ. Wang L, et al. Among authors: papa fr. Nat Chem Biol. 2012 Dec;8(12):982-9. doi: 10.1038/nchembio.1094. Epub 2012 Oct 21. Nat Chem Biol. 2012. PMID: 23086298 Free PMC article.

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