Ruetz M - Search Results

1

Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.

Ruetz M, Campanello GC, Purchal M, Shen H, McDevitt L, Gouda H, Wakabayashi S, Zhu J, Rubin EJ, Warncke K, Mootha VK, Koutmos M, Banerjee R. Ruetz M, et al. Science. 2019 Nov 1;366(6465):589-593. doi: 10.1126/science.aay0934. Science. 2019. PMID: 31672889 Free PMC article.

2

Access to organometallic arylcobaltcorrins through radical synthesis: 4-ethylphenylcobalamin, a potential "antivitamin B(12)".

Ruetz M, Gherasim C, Gruber K, Fedosov S, Banerjee R, Kräutler B. Ruetz M, et al. Angew Chem Int Ed Engl. 2013 Feb 25;52(9):2606-10. doi: 10.1002/anie.201209651. Epub 2013 Feb 13. Angew Chem Int Ed Engl. 2013. PMID: 23404623 Free PMC article.

3

Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.

Gherasim C, Ruetz M, Li Z, Hudolin S, Banerjee R. Gherasim C, et al. Among authors: ruetz m. J Biol Chem. 2015 May 1;290(18):11393-402. doi: 10.1074/jbc.M115.637132. Epub 2015 Mar 25. J Biol Chem. 2015. PMID: 25809485 Free PMC article.

4

A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin.

Ruetz M, Kumutima J, Lewis BE, Filipovic MR, Lehnert N, Stemmler TL, Banerjee R. Ruetz M, et al. J Biol Chem. 2017 Apr 21;292(16):6512-6528. doi: 10.1074/jbc.M116.770370. Epub 2017 Feb 28. J Biol Chem. 2017. PMID: 28246171 Free PMC article.

5

Coordination chemistry controls the thiol oxidase activity of the B₁₂-trafficking protein CblC.

Li Z, Shanmuganathan A, Ruetz M, Yamada K, Lesniak NA, Kräutler B, Brunold TC, Koutmos M, Banerjee R. Li Z, et al. Among authors: ruetz m. J Biol Chem. 2017 Jun 9;292(23):9733-9744. doi: 10.1074/jbc.M117.788554. Epub 2017 Apr 25. J Biol Chem. 2017. PMID: 28442570 Free PMC article.

6

Antivitamin B₁₂ Inhibition of the Human B₁₂ -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate.

Ruetz M, Shanmuganathan A, Gherasim C, Karasik A, Salchner R, Kieninger C, Wurst K, Banerjee R, Koutmos M, Kräutler B. Ruetz M, et al. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7387-7392. doi: 10.1002/anie.201701583. Epub 2017 May 23. Angew Chem Int Ed Engl. 2017. PMID: 28544088 Free PMC article.

7

Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B₁₂ as a Cofactor Conservation Strategy.

Campanello GC, Ruetz M, Dodge GJ, Gouda H, Gupta A, Twahir UT, Killian MM, Watkins D, Rosenblatt DS, Brunold TC, Warncke K, Smith JL, Banerjee R. Campanello GC, et al. Among authors: ruetz m. J Am Chem Soc. 2018 Oct 17;140(41):13205-13208. doi: 10.1021/jacs.8b08659. Epub 2018 Oct 8. J Am Chem Soc. 2018. PMID: 30282455 Free PMC article.

8

Allosteric Regulation of Oligomerization by a B₁₂ Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria.

Ruetz M, Campanello GC, McDevitt L, Yokom AL, Yadav PK, Watkins D, Rosenblatt DS, Ohi MD, Southworth DR, Banerjee R. Ruetz M, et al. Cell Chem Biol. 2019 Jul 18;26(7):960-969.e4. doi: 10.1016/j.chembiol.2019.03.014. Epub 2019 May 2. Cell Chem Biol. 2019. PMID: 31056463 Free PMC article.

9

The human B₁₂ trafficking protein CblC processes nitrocobalamin.

Mascarenhas R, Li Z, Gherasim C, Ruetz M, Banerjee R. Mascarenhas R, et al. Among authors: ruetz m. J Biol Chem. 2020 Jul 10;295(28):9630-9640. doi: 10.1074/jbc.RA120.014094. Epub 2020 May 26. J Biol Chem. 2020. PMID: 32457044 Free PMC article.

10

Chlorocob(II)alamin Formation Which Enhances the Thiol Oxidase Activity of the B₁₂-Trafficking Protein CblC.

Li Z, Greenhalgh ED, Twahir UT, Kallon A, Ruetz M, Warncke K, Brunold TC, Banerjee R. Li Z, et al. Among authors: ruetz m. Inorg Chem. 2020 Nov 2;59(21):16065-16072. doi: 10.1021/acs.inorgchem.0c02653. Epub 2020 Oct 19. Inorg Chem. 2020. PMID: 33074687 Free PMC article.

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