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A conserved miRNA-183 cluster regulates the innate antiviral response.
Singaravelu R, Ahmed N, Quan C, Srinivasan P, Ablenas CJ, Roy DG, Pezacki JP. Singaravelu R, et al. Among authors: roy dg. J Biol Chem. 2019 Dec 20;294(51):19785-19794. doi: 10.1074/jbc.RA119.010858. Epub 2019 Nov 6. J Biol Chem. 2019. PMID: 31694919 Free PMC article.
MicroRNAs regulate the immunometabolic response to viral infection in the liver.
Singaravelu R, O'Hara S, Jones DM, Chen R, Taylor NG, Srinivasan P, Quan C, Roy DG, Steenbergen RH, Kumar A, Lyn RK, Özcelik D, Rouleau Y, Nguyen MA, Rayner KJ, Hobman TC, Tyrrell DL, Russell RS, Pezacki JP. Singaravelu R, et al. Among authors: roy dg. Nat Chem Biol. 2015 Dec;11(12):988-93. doi: 10.1038/nchembio.1940. Epub 2015 Oct 19. Nat Chem Biol. 2015. PMID: 26479438
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.
Wedge ME, Jennings VA, Crupi MJF, Poutou J, Jamieson T, Pelin A, Pugliese G, de Souza CT, Petryk J, Laight BJ, Boileau M, Taha Z, Alluqmani N, McKay HE, Pikor L, Khan ST, Azad T, Rezaei R, Austin B, He X, Mansfield D, Rose E, Brown EEF, Crawford N, Alkayyal A, Surendran A, Singaravelu R, Roy DG, Migneco G, McSweeney B, Cottee ML, Jacobus EJ, Keller BA, Yamaguchi TN, Boutros PC, Geoffrion M, Rayner KJ, Chatterjee A, Auer RC, Diallo JS, Gibbings D, tenOever BR, Melcher A, Bell JC, Ilkow CS. Wedge ME, et al. Among authors: roy dg. Nat Commun. 2022 Apr 7;13(1):1898. doi: 10.1038/s41467-022-29526-8. Nat Commun. 2022. PMID: 35393414 Free PMC article.
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic AHF, Kress A, Carter-Timofte ME, Holm E, van der Horst D, Kollmann CF, Liu Z, Wang C, Hoang HD, Kovalenko E, Chrysopoulou M, Twayana KS, Ottosen RN, Svenningsen EB, Begnini F, Kiib AE, Kromm FEH, Weiss HJ, Di Carlo D, Muscolini M, Higgins M, van der Heijden M, Bardoul A, Tong T, Ozsvar A, Hou WH, Schack VR, Holm CK, Zheng Y, Ruzek M, Kalucka J, de la Vega L, Elgaher WAM, Korshoej AR, Lin R, Hiscott J, Poulsen TB, O'Neill LA, Roy DG, Rinschen MM, van Montfoort N, Diallo JS, Farin HF, Alain T, Olagnier D. Kurmasheva N, et al. Among authors: roy dg. Nat Commun. 2024 May 15;15(1):4096. doi: 10.1038/s41467-024-48422-x. Nat Commun. 2024. PMID: 38750019 Free PMC article.
Murine Tumor Models for Oncolytic Rhabdo-Virotherapy.
Falls T, Roy DG, Bell JC, Bourgeois-Daigneault MC. Falls T, et al. Among authors: roy dg. ILAR J. 2016;57(1):73-85. doi: 10.1093/ilar/ilv048. ILAR J. 2016. PMID: 27034397 Free PMC article.
Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity.
Bourgeois-Daigneault MC, Roy DG, Falls T, Twumasi-Boateng K, St-Germain LE, Marguerie M, Garcia V, Selman M, Jennings VA, Pettigrew J, Amos S, Diallo JS, Nelson B, Bell JC. Bourgeois-Daigneault MC, et al. Among authors: roy dg. Mol Ther Oncolytics. 2016 Feb 17;3:16001. doi: 10.1038/mto.2016.1. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 27119116 Free PMC article.
Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination.
Roy DG, Geoffroy K, Marguerie M, Khan ST, Martin NT, Kmiecik J, Bobbala D, Aitken AS, de Souza CT, Stephenson KB, Lichty BD, Auer RC, Stojdl DF, Bell JC, Bourgeois-Daigneault MC. Roy DG, et al. Nat Commun. 2021 May 11;12(1):2626. doi: 10.1038/s41467-021-22929-z. Nat Commun. 2021. PMID: 33976179 Free PMC article.
47 results