Jacks T - Search Results

1

Identification of DHODH as a therapeutic target in small cell lung cancer.

Li L, Ng SR, Colón CI, Drapkin BJ, Hsu PP, Li Z, Nabel CS, Lewis CA, Romero R, Mercer KL, Bhutkar A, Phat S, Myers DT, Muzumdar MD, Westcott PMK, Beytagh MC, Farago AF, Vander Heiden MG, Dyson NJ, Jacks T. Li L, et al. Among authors: jacks t. Sci Transl Med. 2019 Nov 6;11(517):eaaw7852. doi: 10.1126/scitranslmed.aaw7852. Sci Transl Med. 2019. PMID: 31694929 Free PMC article.

2

Tumor induction and tissue atrophy in mice lacking E2F-1.

Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ. Yamasaki L, et al. Among authors: jacks t. Cell. 1996 May 17;85(4):537-48. doi: 10.1016/s0092-8674(00)81254-4. Cell. 1996. PMID: 8653789 Free article.

3

Targeted disruption of p107: functional overlap between p107 and Rb.

Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T. Lee MH, et al. Among authors: jacks t. Genes Dev. 1996 Jul 1;10(13):1621-32. doi: 10.1101/gad.10.13.1621. Genes Dev. 1996. PMID: 8682293 Free article.

4

Shared role of the pRB-related p130 and p107 proteins in limb development.

Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T. Cobrinik D, et al. Among authors: jacks t. Genes Dev. 1996 Jul 1;10(13):1633-44. doi: 10.1101/gad.10.13.1633. Genes Dev. 1996. PMID: 8682294 Free article.

5

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

Johnson L, Greenbaum D, Cichowski K, Mercer K, Murphy E, Schmitt E, Bronson RT, Umanoff H, Edelmann W, Kucherlapati R, Jacks T. Johnson L, et al. Among authors: jacks t. Genes Dev. 1997 Oct 1;11(19):2468-81. doi: 10.1101/gad.11.19.2468. Genes Dev. 1997. PMID: 9334313 Free PMC article.

6

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice.

Yamasaki L, Bronson R, Williams BO, Dyson NJ, Harlow E, Jacks T. Yamasaki L, et al. Among authors: jacks t. Nat Genet. 1998 Apr;18(4):360-4. doi: 10.1038/ng0498-360. Nat Genet. 1998. PMID: 9537419

7

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.

McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T. McClatchey AI, et al. Among authors: jacks t. Genes Dev. 1998 Apr 15;12(8):1121-33. doi: 10.1101/gad.12.8.1121. Genes Dev. 1998. PMID: 9553042 Free PMC article.

8

Modeling human lung cancer in mice: similarities and shortcomings.

Tuveson DA, Jacks T. Tuveson DA, et al. Among authors: jacks t. Oncogene. 1999 Sep 20;18(38):5318-24. doi: 10.1038/sj.onc.1203107. Oncogene. 1999. PMID: 10498884 Review.

9

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, Tuveson DA, Jacks T. Johnson L, et al. Among authors: jacks t. Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129. Nature. 2001. PMID: 11323676

10

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.

Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. Jackson EL, et al. Among authors: jacks t. Genes Dev. 2001 Dec 15;15(24):3243-8. doi: 10.1101/gad.943001. Genes Dev. 2001. PMID: 11751630 Free PMC article.

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